摘要
目的:探讨银翘温胆汤对放射性肺炎患者降钙素原(PCT)、白细胞(WBC)和C反应蛋白(CRP)水平的影响。方法:选取符合纳入标准的放射性肺炎患者90例随机分为治疗组和对照组,各45例。对照组给予常规西药治疗,治疗组在对照组的基础上加用银翘温胆汤治疗,对比分析两组患者临床有效率、PCT、WBC及CRP水平。结果:治疗组的总有效率为91.1%(41/45),对照组的总有效率为75.6%(34/45),差异有统计学意义(P<0.05)。与治疗前比较,两组患者治疗后PCT、WBC及CRP水平均显著降低(P<0.05),且治疗组优于对照组(P<0.05)。结论:银翘温胆汤能有效降低放射性肺炎患者PCT、WBC及CRP水平,治疗效果优于常规西药治疗,值得推广应用,且PCT、WBC和CRP对放射性肺炎的诊断和治疗具有重要的临床指导价值。
Abstract：Objective： To discuss the effect of Yinqiao Wendan Decoction on the levels of procalcitonin（PCT）,white blood cell（WBC） and C reactive protein（CRP） in patients with radiation pneumonitis. Methods： 90 patients with radiation pneumonitis were randomly divided into the treatment group （ n = 45） and the controlgroup（n = 45）. The control group was given conventional western therapy, on which basis, the treatmentgroup was additionally given Yinqiao Wendan Decoction. The clinical therapeutic effect and the levels of PCT,WBC and CRP were compared between the two groups. Results： The total efficiency of the treatment groupwas 91. 1%（41 / 45）, which was significantly higher than 75. 6% （34 / 45） of the control group（P 〈 0. 05）.The levels of PCT, WBC and CRP were decreased significantly after the treatment in the two groups（P 〈0, 05）, for which, the treatment group was better than the control group（P 〈 0. 05）. Conclusion： YinqiaoWendan Decoction can effectively improve the therapeutic effect and reduce the levels of PCT ,WBC and CRPin patients with radiation pneumonitis, which is superior to the simple application of conventional western medicine. It is worthy of clinical popularization and application. Furthermore, te values of PCT, WBC, and CRPhave a significant guidance for dignosis and treatment of radiation pneumonitis.
作者
马东阳
耿良
胡彦辉
崔庆丽
刘怀民
MA Dongyang;GENG Liang;HU Yanhui;CUI Qingli;LIU Huaimin(Cancer Hospital Affiliated to Zhengzhou University,Zhengzhou 450008,Chin)
出处
《中医药信息》
2018年第3期98-101,共4页
Information on Traditional Chinese Medicine
基金
国家自然科学基金项目(No.81473638)
