摘要
目的分析肝硬化腹水发生自发细菌性腹膜炎(SBP)的外周血辅助检查结果及相关因素。方法选择132例肝硬化腹水患者,观察外周血辅助检查结果,对可能引起SBP的相关危险因素进行分析。结果发生SBP患者的外周血WBC计数、NEUT计数、CD8+T淋巴细胞、CRP、m CD14指数、PCT及IL-6水平明显高于未发生患者(P<0.05)。单因素分析显示,血清总胆红素、血清白蛋白、腹水WBC、消化道出血史与肝硬化腹水发生SBP密切相关(P<0.05)。多因素Logistic回归分析显示,血清白蛋白<28 g/L和消化道出血史是引起肝硬化腹水发生SBP的独立危险因素(P<0.05)。结论监测外周血感染相关指标有助于SBP的早期辅助诊断,同时血清白蛋白<28 g/L和消化道出血史是引起肝硬化腹水发生SBP的独立危险因素,临床应增强对上述指标的监测。
Objective To analyze the peripheral blood auxiliary examination results and related factors of spontaneousbacterial peritonitis （SBP） in cirrhotic ascites. Methods A total of 132 patients with cirrhotic ascites in our hospital wereselected. The peripheral blood test results were observed and the risk factors that may cause SBP were analyzed. ResultsThe peripheral blood WBC counts, NEUT counts, CD8＋T lymphocytes, CRP, mCD14 index, PCT and IL-6 levels in patientswith SBP were significantly higher than those in non-invasive patients（P〈0.05）. The univariate analysis showed that serumtotal bilirubin, serum albumin, ascites WBC and gastrointestinal bleeding history were closely related to SBP in cirrhosisascites （P〈0.05）. The multivariate Logistic regression analysis showed that serum albumin〈28 g/L and gastrointestinalbleeding history were independent risk factors for SBP in patients with cirrhosis ascites （P〈0.05）. Conclusion Monitoringrelated indicators of peripheral blood infections helps early diagnosis of SBP, at the same time, serum albumin〈28 g/L andgastrointestinal bleeding history were the independent risk factors of SBP in cirrhosis ascites, it should strengthen themonitoring of these indicators in clinic.
作者
龚本冰迪
王敏莉
GONG Ben-bing-di;WANG Min-li(Gastroenterology Department,Taizhou People＇s Hospital,Taizhou 225300;No.1 Internal Medicine Department,the Hospital of Baishui County,Weinan 715600,China)
出处
《临床医学研究与实践》
2018年第22期110-111,共2页
Clinical Research and Practice
