摘要
目的分析甘胆酸(CG)在肝炎检测中的应用价值。方法方便选取2017年7—12月该医院诊断为急性肝炎患者50例、慢性肝炎患者50例、肝硬化患者50例、肝内胆管结石患者50例、肝肿瘤患者50例、体检健康300例,合计550名对象进行了甘胆酸检测,按照疾病的类型进行分组。结果急性肝炎、慢性肝炎、肝硬化、肝内胆管结石、肝肿瘤患者CG水平高于健康体检对象,慢性肝炎、急性肝炎患者CG水平低于肝肿瘤,肝肿瘤患者CG水平低于肝硬化患者、肝内胆管结石患者,差异有统计学意义(P<0.05)。鉴别诊断慢性肝炎与其他类型的肝病,截断值为2.65 mg/L,诊断效用指标为灵敏度68.0%(34/50)、特异度73.6%(184/250)、阳性预测值34.0%(34/100)、阴性预测值92.0%(184/200)、符合率72.7%(218/300)。误诊对象主要为早期以及失代偿期肝硬化、肝肿瘤、急性肝炎康复期对象。结论甘胆酸(CG)在肝炎诊断中有一定的价值,可以有效的鉴别诊断其他类型的肝损伤疾病,考虑到失代偿期肝硬化、肝肿瘤、急性肝炎康复期对象,对于无明显症状、病史对象诊断可进一步提高。
Objective To analyze the application value of CG in testing the hepatitis. Methods From July to Decaber2017,50 cases pationts with acute hepatitis, 50 cases pationts with chronic hepatitis, 50 cases pationts with cirrhosis,50 cases pationts with hepatolith, 50 cases with liver tumor and 300 healthy people（550 cases in total） were randomly selection for glycocholic acid test and grouped according to the type of diseases. Results The CG levels of acute hepatitis,chronic hepatitis, cirrhosis, hepatolith, liver tumor were higher than the healthy physical examination objects and the acute hepatitis and chronic hepatitis were lower than the liver tumor, and the liver tumor was lower than the cirrhosis and hepatolith, and the difference was statistically significant（P〈0.05）, in differential diagnosis of chronic hepatitis and the other types of liver diseases, the truncated value, sensitivity, specificity, positive predicative value, negative predicative value and coincidence rate were respectively 2.65 mg/L, 68.0%（34/50）,73.6%（184/250）,34.0%（34/100）, 92.0%（184/200） and 72.7%（218/300）, and the misdiagnosis objects were mainly with early and decompensated cirrhosis, liver tumor and acute hepatitis rehabilitation patients. Conclusion The CT in diagnosis of hepatitis has a certain value, which can effectively diagnose the other types of liver injuries, and diagnosis can be further improved for objects without obvious symptoms and disease history considering the decompensated cirrhosis, liver tumor and acute hepatitis rehabilitation objects.
作者
李松鹏
景红艳
LI Song-peng;JING Hong-yan(Department of Clinical laboratory,Kunming Third People＇s Hospital,Kunming,Yunnan Province,650041 China;De- partment of Clinical Laboratory,Jinning District People＇ s Hospital,Kunnfing,Yunnan Province,650600 China)
出处
《中外医疗》
2018年第17期190-191,198,共3页
China & Foreign Medical Treatment
关键词
肝炎
甘胆酸
诊断
Hepatitis
CG
Diagnosis
