摘要
目的了解新疆乌鲁木齐市某社区维吾尔族、汉族育龄期女性甲状腺疾病的检出情况。方法在新疆乌鲁木齐市2个维吾尔族、汉族混居区采用横断面整群抽样方法随机抽取2080名社区居民,其中资料完整的育龄期女性一共619名(维/汉:388/231),年龄18~45岁,平均(35.15±6.982)岁,静脉血测定促甲状腺素(TSH)、血清游离甲状腺素(FT4)、游离三碘甲状腺原氨酸(FT3)、甲状腺球蛋白抗体(TgAb)、甲状腺过氧化物酶抗体(TPOAb),B超检测有无甲状腺结节。结果 (1)维吾尔族、汉族人群中甲状腺功能亢进(甲亢)检出率分别是1.5%、0.4%;亚临床甲状腺功能亢进(亚甲亢)检出率分别是1.3%、0%;甲状腺功能减低(甲减)检出率分别是4.4%、0.9%;亚临床甲状腺功能减退(亚甲减)检出率分别是22.7%、22.9%;甲状腺结节检出率分别是16.2%、16.9%,其中单发结节检出率分别是12.4%、13.9%,多发结节检出率分别是3.9%、3.0%;TPOAb阳性率分别是24.6%、32.9%,TgAb阳性率分别是49.5%、22.9%;TgAb合并TPOAb阳性率分别是16.0%、17.7%。(2)维吾尔族中甲减检出率及TgAb阳性率明显高于汉族(χ~2=4.891,P=0.027;χ~2=42.651,P=0.000),汉族中TPOAb阳性率明显高于维吾尔族(χ~2=4.889,P=0.027)。结论乌鲁木齐某社区育龄期女性甲状腺疾病检出情况不容乐观,维吾尔族中甲减检出率及TgAb阳性率明显高于汉族。汉族中TPOAb阳性率明显高于维吾尔族。
Objective To investigate the prevalence of thyroid diseases in Uyghur and Hart women in childbearing age in a community of Urumqi. Methods A total of 2080 community residents were randomly selected from 2 areas in Urumqi, Xinjiang, with a total of 619 women of childbearing age（Uyghur/Han： 388/231 ）, aged from 18 to 45 years old, the average years old was （35.15 ＋ 6.982）, the markers of thyroid function such as thyroid stimulating hormone （TSH）, blood serum free thyroxine （FT4）, three thyroid free ammonia acid fiT3）, thyroglobulin antibody （TgAb）, thyroid peroxidase antibody （TPOAb） were determind with the electrochemiluminescence immunoassay, B-ultrasound was used to detect thyroid nodules. Results 1.In Uyghur and Han population, the detection rates of hyperthyroidism were 1.5%, 0.4%,respectively; The detection rates of subclinical hyperthyroidism were 1.3%, 0%,respectively; The detection rates of hypothyroidism were 4.4%, 0.9%; The detection rates of subclinical hypothyroidism were 22.7%, 22.9%; The detection rates of thyroid nodules were 16.2%, 16.9%, one single nodule detection rates were 12.4%, 13.9%, multiple nodules detection rate were 3.9%, 3.0%; The positive rates of TPOAb were 24.6%, 32.9%.;The positive rates of TgAb were d9.5%, 22.9%; The positive rate of TgAb combined with TPOAb were 16% and 17.7%. 2. The detection rate of hypothyroidism and the positive rate of TgAb in Uyghur weresignificantly higher than those in Han nationality ,（χ2=4.891, P =0.027;χ2=42.651, P =0.000）, and the positive rate of TPOAb in Han was significantly higher than that of Uyghur nationality （χ2=4.889, P =0.027）. Condusiort The detection of thyroid diseases in a community in Urumqi is not optimistic, and the detection rate of hypothyroidism and the positive rate of TgAb in Uyghur were significantly higher than that of Han nationality, the positive rate of TPOAb in Han nationality was higher than that of Uyghur.
作者
伊合巴兰.阿不都热合曼
郭艳英
王新玲
罗蕴之
衣巴地古丽.库吐鲁克
木尼拉.阿不都乃依木
邢淑清
辛亮
Yihebalan·Abdureheman;GUO Yanying;WANG Xinling;LUO Yunzhi;Yibadiguli· Kutulike;Munila· Abudunaiyimu;XING Shuqing;XIN Liang(Postgraduate college of Xinjiang Medical University,Xinjiang,Urumqi,Xinjiang,830054,China;People＇s Hospital of Xinjiang Uyghur Autonomous Region,Xinjiang,Urumqi,Xinjiang,830001,Chin)
出处
《新疆医学》
2018年第5期523-526,共4页
Xinjiang Medical Journal
基金
新疆维吾尔自治区科技基础条件平台建设项目(81560136)
