摘要
目的应用超声心动图对肺动脉高压患者经皮介入术前、术后心脏结构及功能进行比较，探讨经皮介入治疗方法的短期效果。方法选取我院行经皮肺动脉介入术治疗的肺动脉高压患者8例，均为中重度肺动脉高压。超声心动图测量参数包括右心室横径（RVD）、左心室横径（LVD）、右心房横径（RAD）、左心房横径（LAD）、肺动脉主干内径（DMPA）、左室偏心指数（E1）、左室射血分数（LVEF）、右室收缩压（RVSP）、三尖瓣环收缩期位移（TAPSE）、右室面积变化分数（RVFAC）、三尖瓣环收缩期峰值速度（s＇）、右心做功指数（RIMP）及右室游离壁纵向应变（RVLSFW）。患者介入术后随访时间中位数为98d。结果①本组8例患者未出现明显严重并发症，仅有1例患者置入支架过程中有轻微内膜撕脱。②肺动脉高压患者介入术前RVSP明显升高，RVD／LVD增大（P〈0．05）。介入治疗术后患者RVSP下降明显（P〈0．01），RVD／LVD减小（P〈0．05）。③肺动脉高压患者介入治疗后随访结果显示RVFAC、RIMP、s＇及RVLSFW改善（均P〈0．05）。结论超声心动图能够评价肺动脉高压介人治疗的近期效果，提示肺动脉狭窄介入治疗近期有效且安全。
Objective To evaluate and compare cardiac structure and function pre- and post- percutaneous interventional treatment of pulmonary hypertension （PH） using echocardiography. Methods Eight female patients received percutaneous interventional treatment in our hospital were enrolled. All of them were suffered moderate to severe PH. Echocardiographic parameters included： right ventricular diameter （RVD）, left ventricular diameter （LVD）, right atrial diameter （RAD）, left atrial diameter （LAD）, main pulmonary arterial diameter （DMPA）, left ventricular eccentric index （EI）, left ventricular ejection fraction （LVEF）, right ventricular systolic pressure （RVSP）, tricuspid annular plane systolic excursion （TAPSE）, right ventricular fractional area change （RVFAC）, tissue Doppler-derived tricuspid lateral annular systolic velocity （s＇）, right ventricular index of myocardial performance （RIMP） and right ventricular free wall longitudinal strain （RVLSFw）. The median time for follow-up after interventional treatment was 98 d. Results ①In our study, 8 patients had no significant serious complications, and only one patient had mild intimal avulsion during stenting. ②RVSP and RVD/LVD increased significantly before intervention in patients with PH （ P 〈 0.05）. After interventional treatment, RVSP （ P 〈 0.01 ） and RVD/LVD decreased significantly （ P 〈0.05）. ③The result of follow-up showed that RVFAC, RIMP, s＇ and RVLSFW improved significantly（ P 〈0.05）. Conclusions Echocardiography could evaluate the recent effect of interventional treatment and illustrates that the interventional treatment for pulmonary artery stenosis is effective and safe.
作者
李一丹
杨媛华
王剑锋
龚娟妮
王怡丹
姜哲
吕秀章
Li Yidan;Yang Yuanhua;Wang Jianfeng;Gong Juanni;Wang Yidan;Jiang Zhe;Lyu Xiuzhang(Department of Echocardiography,Beijing Chao-Yang Hospital,Capital Medical University,Beijing 100020,China)
出处
《中华超声影像学杂志》
CSCD
北大核心
2018年第7期565-568,共4页
Chinese Journal of Ultrasonography
基金
国家自然科学基金项目（81401420）
北京市“215”高层次卫生技术人才学科骨干项目（2014-3-027）
朝阳医院1351人才培养计划（CYXX-2017-27）
关键词
超声心动描记术
高血压
肺性
经皮介入治疗
Echocardiography
Hypertension
pulmonary
Percutaneous intervention
