摘要
足细胞是位于肾小囊脏层上的上皮细胞,其分化程度极高,属于肾小球的终末细胞,有多种肾脏疾病与足细胞损伤有关。目前已有多项研究探明影响足细胞分化过程的因素,期望通过研究分化过程影响因子而对足细胞病有进一步的了解和认识,有助于其诊断和治疗。本文就近几年对影响足细胞分化的几种因素研究作一综述。
Podocytes are epithelial cells located in the renal vesicle. It has a very high degree of differentiation and belongs to the terminal cells of the glomeruli. There are a variety of renal diseases related to the injury of podocytes. At present, a number of studies have been made to identify the factors affecting the differentiation of podocytes. Investigating the factors affecting the differentiation process will facilitate the understanding of podoeyte disease and improve diagnose and treatment. In this paper, several factors affecting podocyte differentiation in recent years were reviewed.
作者
顾靖钏
何瑞
甘为华
GU Jingchuan;HE Rui;GAN Weihua(Department of Clinical Medicine,Nanjing Medical University,Nanjing,Jiangsu 210003,China;Department of Pediatric Nephrology,the Second Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu 210003)
出处
《徐州医科大学学报》
CAS
2018年第7期486-490,共5页
Journal of Xuzhou Medical University
基金
江苏省自然科学基金(81670650)
江苏省高等学校大学生创新创业训练计划项目(201710312010Z)
关键词
足细胞
细胞分化
机制
podocyte
cell differentiation
mechanism