摘要3D打印( three - dimensional printing)技术又称三维打印技术,是一种起步于20世纪90年代的以数字模型数据为基础,计算机辅助设计图样,使用可粘合材料,通过逐层打印叠加的方式制造物体模型的技术。但是由于生产成本高、技术不成熟等多种原因,3D打印在中国一直处于实验室研究阶段,研究的领域也比较局限,直到2012年3D打印技术才广泛进入人们视野。
4KRUTH J P,LEU M C,NAKAGAWA T.Progress in additive manufacturing and rapid prototyping[J].Annals of CIRP,1998,47(2):525-540.
5KIM S S,UTSUNOMIYA H,KOSKI J A,et al.Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scaffold with an intrinsic network of channels[J].Annals of Surgery,1998,228(1):8-13.
6LAM C X F,MO X M,TEOH S H,et al.Scaffold development using 3D printing with a starch-based polymer[J].Materials Science & Engineering C-Biomimetic and Supramolecular Systems,2002,20(1-2):49-56.
7SHERWOOD J K,RILEY S L,PALAZZOLO R,et al.A three-dimensional osteochondral composite scaffold for articular cartilage repair[J].Biomaterials,2002,23(24):4 739-4 751.
8LANDERS R,MULHAUPT R.Desktop manufacturing of complex objects,prototypes and biomedical scaffolds by means of computer-assisted design combined with computer-guided 3D plotting of polymers and reactive oligomers[J].Macromolecular Materials and Engineering,2000,282(9):17-21.
9LANDERS R,HUBNER U,SCHMELZEISEN R,et al.Rapid prototyping of scaffolds derived from thermoreversible hydrogels and tailored for applications in tissue engineering[J].Biomaterials,2002,23(23):4 437-4 447.