摘要
目的:探讨孟鲁司特与氯苯那敏(商品名扑尔敏)治疗小儿咳嗽变异性哮喘的临床效果。方法:选择63例变异性哮喘患儿随机分为观察组和对照组。两组患儿均给予沙丁胺醇片等药物治疗,对照组患儿同时给予氯苯那敏治疗,观察组患儿同时给予孟鲁司特咀嚼片治疗。两组患儿连续治疗4周,观察两组咳嗽消失时间,治疗结束后评定临床效果,记录不良反应发生情况。结果:观察组咳嗽消失时间低于对照组,两组比较差异有统计学意义(P<0.05)。观察组治疗后的总有效率高于对照组,两组比较差异有统计学意义(P<0.05)。两组均没有出现严重不良反应,均完成疗程。结论:孟鲁司特治疗小儿咳嗽变异性哮喘效果显著,值得借鉴。
Objective To explore the clinical effect of montelukast and chlorpheniramine in treatment of children with cough variant asthma. Method 63 children with variant asthma in our hospital were selected and randomly divided into observation group and control group. Two groups were given aminophylline in the treatment,the control group were given chlorpheniramine The Children in the observation group were given montelukast chewable tablets. The two groups were treated for 4 weeks. The disappearance time of cough and pulmonary wheeze in the two groups were observed. The clinical effect was evaluated after treatment. The incidence of adverse reactions was recorded. Results The disappearing time of cough in the observation group were lower than those in the control group,the difference was statistically significant（ P〈0.05）. The total effective rate（ significant efficiency and effective rate） of the observation group after treatment was higher than that of the control group,the difference was statistically significant（ P〈0.05）. There were no serious adverse reactions in the two groups,and all the patients completed the course of treatment. Conclusion montelukast is effective in the treatment of cough variant asthma in children,and is worthy of reference.
作者
王莹莹
FANG Ying-ying(Naihai Hospital of Southern Medical Urliversity,Foshan 528244,China)
出处
《吉林医学》
CAS
2018年第6期1085-1087,共3页
Jilin Medical Journal
