摘要
目的探讨血清淀粉样蛋白A(SAA)、中性粒细胞与淋巴细胞比值(NLR)对急性胰腺炎严重程度的预测价值。方法回顾性分析2015年1月~2017年5月佛山市高明区人民医院收治的116例急性胰腺炎患者的临床资料,按疾病严重程度分为SAP组(34例)、MSAP组(47例)和MAP组(35例),对患者的一般资料、SAA、白细胞计数(WBC)及NLR进行统计分析。结果 3组间的SAA、NLR比较,差异有统计学意义(P<0.05);进一步两两比较显示,SAP组高于MSAP组,且SAP组和MSAP组均高于MAP组,差异均有统计学意义(P<0.05)。SAA、WBC、NLR对SAP预测的ROC曲线下面积分别为0.912、0.776、0.842。SAA、WBC、NLR对MSAP+SAP预测的ROC曲线下面积分别为0.839、0.799、0.811。结论 SAA、NLR对急性胰腺炎严重程度的预测具有一定的价值。
Objective To investigate the predictive value of serum amyloid A（SAA）,neutrophilto-lymphocyte rate（NLR） for the severity of acute pancreatitis.Methods The clinical data of 116 patients with acute pancreatitis admitted to Gaoming People＇s Hospital of Foshan City from January 2015 to May 2017 were retrospectively analyzed and divided into SAP group（34 cases）,MSAP group（47 cases） and MAP group（35 cases） according to the severity of the disease.The general information of patients,SAA,white blood cell count（WBC） and NLR were analyzed.Results There were statistically significant differences in NLR and SAA among the three groups（P〈0.05）.Further comparision showed that the indicators above in SAP group were higher than that of MSAP group,both SAP group and MSAP group were higher than that of MAP group,with statistically significant differences（P 0.05）.The areas of SAA,WBC and NLR under the ROC curve predicted by SAP were 0.912,0.776 and 0.842 respectively.The areas of SAA,WBC and NLR under ROC curve were 0.839,0.799 and 0.811 for MSAP＋SAP.Conclusion SAA and NLR have a certain value in predicting the severity of acute pancreatitis.
作者
谷小玉
黄尚书
梁伟新
刘小真
冯伟兆
赖勇强
朱明章
李志宏
GU Xiaoyu HUANG Shangshu LIANG Weixin LIU Xiaozhen FENG Weizhao LAI Yongqiang ZHU Mingzhang LI Zhihong(Department of General Surgery,Gaoming People＇s Hospital of Foshan City,Guangdong Province,Foshan 528500,Chin)
出处
《中国医药导报》
CAS
2018年第16期63-66,共4页
China Medical Herald
基金
广东省佛山市医学科研项目(20170392)
广东省佛山市医学类科技攻关项目(2015AB000964)
广东省佛山市省级医学重点专科培育项目(fspy3-2015040)
