摘要
目的应用实时三维超声(RT-3DE)及组织速度向量(VVI)技术评价右心室整体及局部收缩功能,预测其在肺动脉高压(PH)患者右心功能衰竭中的价值。方法选取我院诊断的PH患者86例,根据肺动脉收缩压(PASP)分为轻中度组、重度组,每组43例,选择体检健康人35例作为对照组,应用实时三维超声定量分析右心室三维射血分数(3D-RVEF),右心室三维每搏量(3D-RVSV),右心室三维舒张末容积(3D-RVEDV),右心室三维收缩末容积(3D-RVESV),采用VVI技术分析右心室六个节段心肌纵向应变(L-S)、应变率(L-SR)、整体应变(Globle S)及应变率(Globle SR),并分析各参数之间的关系。结果与对照组比较,轻中度组和重度组3D-RVEF逐渐减低,3DRVEDV、3D-RVESV及3D-RVSV增高(P<0.01);3组右心室室间隔心尖段的L-SR比较差异无统计学意义(P>0.05),与对照组比较,两PH组右心室其余各节段L-S,L-SR均减低(P<0.05),与轻中度组比较,重度组右心室L-S及L-SR降低更明显(P<0.05),与对照组比较,两PH组右心室其余各节段L-S,L-SR、Globle S及Globle SR均减低(P<0.05),与轻中度组比较,重度组降低更明显(P<0.05),3D-RVEF与Globle S,Globle SR呈正相关。PASP与Globle S,Globle SR呈负相关,但相关性均不强。结论肺动脉高压组右心室整体收缩功能有所降低,随着肺动脉压力逐渐增高,右心室各节段纵向应变及应变率逐渐减低,但是在不同程度PH组中,右心室局部收缩功能变化比整体功能变化更早。
Objective To evaluate the global and regional systolic function of the right ventricle using realtime three-dimensional ultrasound（RT-3 DE）and tissue velocity vector image（VVI）techniques,and to predict its value to patients with pulmonary hypertension（PH）associated with right heart failure.Methods A total of 86 PH patients was selected and divided into two groups according to pulmonary arterial systolic pressure（PASP）：the light-tomoderate PH group mild group and the severe PH group.Totally 43 patients in each group were selected for physical examination.Realtime three-dimensional ultrasound quantitative analysis of right ventricular three-dimensional ejection fraction（3 D-RVEF）,right ventricular three-dimensional stroke volume（3 D-RVSV）,right ventricular threedimensional enddiastolic volume（3 D-RVEDV）,right ventricular three-dimensional endsystolic volume（3 D-RVESV）were analyzed using the VVI technique to analyze the longitudinal myocardial strain（LS）,strain rate（L-SR）global strain（Globle S）and strain rate（Globle SR）in six segments of the right ventricle.The relationship between the parameters was analysed.Results Compared with the control group,3 DRVEF was gradually decreased in the mild-tomoderate group and the severe group,and 3 D-RVEDV,3 D-RVESV,and 3 D-RVSV witnessed increase（P〈0.01）.There was no statistical difference in LSR between the three groups of interventricular septum A.Compared with the control group,the LS and LSR in the left ventricular segments of the right ventricle in both PH groups decreased（P〈0.05）.Compared with the light-to-moderate group,the LS and LSR in the severe group decreased.Compared with the control group,the LS and LSR in the left ventricular segments of the right ventricle in both PH groups decreased（P〈0.05）.Compared with the light-to-moderate group,the LS and LSR in the severe group decreased.3 DRVEF was positively correlated with Globe S and Globle SR.PASP was negatively correlated with Globle S and Globle SR,but the correlation was not strong.Conclusion The systolic function of the right ventricle in the pulmonary arterial hypertension group was reduced.With the increase of the pulmonary artery pressure,the longitudinal strain and strain rate of the right ventricle segments gradually decreased.However,in the groups with different levels of PH,the change of right ventricular local systolic function was earlier that of the overall function.
作者
马惠
张永峰
李慧莉
冯国燕
Ma Hui;Zhang Yongfeng;Li Huili;Fen Guoyan(Department of Function,Lanzhou Traditional Chinese Medicine Hospital,Lanzhou 730050,Chin)
出处
《临床荟萃》
CAS
2018年第6期506-509,514,共5页
Clinical Focus
关键词
超声心动描记术
三维
向量心电描记术
高血压
肺性
心室功能
右
echocardiography
three dimensional
vectorcardiography
hypertension
pulmonary
ventricular function
right
