摘要
目的评价重症真菌性角膜溃疡患者进行自体结膜瓣移植手术的临床效果。方法选取重症真菌性角膜溃疡患者共90例,随机分为药物组和手术组,各45例。药物组给予药物治疗,手术组给予自体结膜瓣移植术治疗。比较两组的临床效果。结果手术组临床效果分布及治愈率均显著优于药物组(P<0.05);治疗后,随着时间的延长,两组患者的视力显著改善(P<0.05);治疗后1周和治疗后1个月,手术组视力显著优于药物组(P<0.05);手术组真菌性眼内炎发生率显著低于药物组(P<0.05)。结论在重症真菌性角膜溃疡患者中自体结膜瓣移植手术效果明显优于药物治疗,还可显著改善视力,避免真菌性眼内炎的发生。
Objective To evaluate the clinical effect of autologous conjunctival flap transplantation in patients withsevere fungal corneal ulcer. Methods A total of 90 patients with severe fungal corneal ulcer were selected and randomlydivided into drug group and operation group, with 45 cases in each group. The drug group was given medication treatment,and the operation group was treated with autologous conjunctival flap transplantation. The clinical effects of the two groupswere compared. Results The distribution of clinical effect and cure rate in the operation group were significantly better thanthose in the drug group（P〈0.05）. After treatment, the visual acuity of the two groups improved significantly（P〈0.05）. At1week and 1 month after treatment, the visual acuity of the operation group were better than those of the drug group （P〈0.05）.The incidence of fungal endophthalmitis in the operation group was significantly lower than that in the drug group（P〈0.05）.Conclusion Autologous conjunctival flap transplantation in patients with severe fungal corneal ulcer has better clinicaleffect compared with medication treatment. It can improve the visual acuity and avoid the occurrence of fungalendophthalmitis.
作者
马艳
丁俊冰
MA Yan;DING Jun-bing(the First People＇s Hospital of Xianyang City,Xianyang 712000,China)
出处
《临床医学研究与实践》
2018年第18期91-92,共2页
Clinical Research and Practice
关键词
自体结膜瓣移植手术
药物治疗
重症真菌性角膜溃疡
autologous conjunctival flap transplantation
medication treatment
severe fungal corneal ulcer
