摘要
目的探讨磁共振检查在筛查脑动脉硬化、脑动脉狭窄及脑白质脱髓鞘中的应用价值,并分析三种疾病的影响因素,从而科学的选择体检项目,以达到早期预防疾病的目的。方法随机抽取2016年1月至12月在郑州大学第一附属医院接受核磁共振脑部检查的997例健康体检者,记录体检者的性别、年龄、体重指数(BMI)、血压、血糖、血脂等基本情况;首先采用检验等进行单因素筛选(α=0.1),再用多因素非条件Logistic回归分别分析三种脑部疾病的影响因素。结果 Logistic回归分析结果显示,在调整其他自变量的影响后,年龄、BMI及收缩压水平可能是导致脑动脉硬化发生的危险因素;年龄及收缩压可能是导致脑动脉狭窄发生的危险因素;性别、年龄和收缩压可能是导致脑脱髓鞘发生的危险因素。结论对存在超重、高血压及年龄、性别等影响因素的健康体检人群应用磁共振筛查脑部相关疾病价值较高,并为制定具体干预措施提供了依据和方向。
Objective To investigate the value of magnetic resonance imaging in screening cerebral arteriosclerosis, arterial stenosis and demyelination, and to analyze the risk factors of three cerebrovascular diseases. Methods Selected 997 cases of physical examination by magnetic resonance imaging in the First Affiliated Hospital of Zhengzhou University from January to December in 2016 randomly. The information included gender, age, body mass index（BMI）, blood pressure, blood sugar, blood lipid and other basic conditions were recorded, test were used to select the single factor（α=0.1） based on the potential risk factors first, and then multivariate logistic regression was used to analyze the influencing factors of the three kinds of cerebrovascular diseases. Results After adjusted for other variables, logistic regression showed that age, BMI and systolic blood pressure may be the risk factors for cerebral arteriosclerosis, age and systolic blood pressure may increase the risk of cerebral artery stenosis; gender, age, and systolic blood pressure may be risk factors for demyelination in the brain. Conclusion The use of MRI for screening brain related diseases in healthy people with overweight, hypertension, age, sex and other factors is of higher value, which provides the basis and direction for choosing health examination items and taking specific intervention measures in the future.
作者
丁素英
赵睿
DING Su-ying;ZHAO Rui(Department of Medical Center,First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)
出处
《中国CT和MRI杂志》
2018年第5期37-39,46,共4页
Chinese Journal of CT and MRI
基金
河南省高等学校重点科研项目计划
项目编号:17A320018
关键词
健康体检
磁共振
脑部相关疾病
影响因素
Physical Examination
Magnetic Resonance Angiography
Cerebrovascular Diseases
Risk Factor
