摘要
目的探究动态增强磁共振成像(DCE-MRI)在直肠癌患者术前中的应用。方法收集2015年12月-2017年12月于信阳市中心医院肿瘤外科诊治的240例直肠癌患者MRI常规及DCE-MRI扫描图像进行回顾性分析,将患者容量转移常数(K^(trans))、速率常数(K_(ep))、EES容积比(V_e)参数结果与肿瘤病理分化程度、Dukes分期、TNM分期及淋巴结转移情况进行对比分析。结果K^(trans)随肿瘤病理分化程度降低、Dukes分期增加、TNM分期增加及淋巴结转移而显著升高,差异有统计学意义(P﹤0.05);K_(ep)、V_e在病理分化程度、Dukes分期、TNM分期及淋巴结转移的差异比较无统计学意义(P﹥0.05)。结论 DCE-MRI可较好地反映肿瘤内部血流动力学情况,其参数K^(trans)值与病理分化程度、Dukes分期、TNM分期及淋巴结转移具一定相关性,对直肠癌术前评估具重要应用价值。
Objective To explore the preoperative application of dynamic contrastenhanced magnetic resonance imaging（DCE-MRI） in patients with rectal cancer. Methods The scan images of MRI routine and DCE-MRI of 240 patients with rectal cancer treated in department of oncology at Xinyang Central Hospital from December 2015 to December 2017 were collected for retrospective analysis. The capacity transfer constant（K（trans））, rate constant（K（ep）） and EES volume ratio（Ve） were analyzed and compared with tumor pathological differentiation, Dukes stage, TNM stage and lymph node metastasis. Results K（trans） was increased significantly with the decreased tumor pathological differentiation, increased Dukes stage and TNM stage and lymph node metastasis（P0.05）. There was no significant difference in pathological differentiation, Dukes stage, TNM stage and lymph node metastasis between K（ep） and Ve（P〉0.05）. Conclusion DCE-MRI can better reflect the hemodynamics within tumor, and its K（trans） value is correlated with the pathological differentiation, Dukes stage, TNM stage and lymph node metastasis, and it has important application value for preoperative evaluation of rectal cancer.
作者
霍亮
杜勇
HUO Liang;DU Yong(Department of Oncology,the Cental Hospital of Xinyang City,Xinyang 464000,Henan Province,China)
出处
《中国CT和MRI杂志》
2018年第6期118-120,140,共4页
Chinese Journal of CT and MRI
关键词
动态增强
磁共振成像
直肠癌
应用价值
Dynamic Contrast-enhanced
Magnetic Resonance Imaging
Rectal Cancer
Application Value
