摘要
目的研究MSCT强化扫描与MRI在评估肝癌微波消融疗效的应用。方法选取2014年6月至2017年6月55例肝癌(73个病灶)患者为研究对象,所有患者均接受微波消融治疗,并在微波消融治疗1个月后行MSCT扫描、MRI检查及血管造影。以血管造影结果为金标准,计算MSCT强化扫描与MRI评估肝癌微波消融疗效的灵敏度、特异度、阳性预测值、阴性预测值、准确性。结果经血管造影证实,73个肝癌病灶,经微波消融治疗,完全消融48个,不完全消融25个。MSCT强化扫描评估肝癌微波消融疗效灵敏度、特异度、阳性预测值、阴性预测值、准确性、Kappa值分别为85.42%、68.0%、83.7%、70.8%、79.5%、0.54。MRI检查评估肝癌微波消融疗效的灵敏度、特异度、阳性预测值、阴性预测值、准确性、Kappa值分别为91.7%、92.0%、95.7%、85.2%、91.8%、0.82。MRI检查评估肝癌微波消融疗效的特异度、准确性显著高于MSCT强化扫描(P<0.05)。结论 MSCT强化扫描与MRI检查均可清晰呈现肝癌微波消融后病灶变化。MRI检查较MSCT强化扫描可以更准确评估肝癌微波消融疗效。
Objective To study the application of MSCT enhanced scan and magnetic resonance imaging(MRI) in evaluating the curative effect of microwave ablation for liver cancer. Methods 55 patients with liver cancer(73 lesions) who were admitted to the hospital from June 2014 to June 2017 were selected as study subjects. All of them were treated by microwave ablation, and MSCT scan, MRI examination and angiography were performed at 1 month after microwave ablation. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of MSCT enhanced scan and MRI in evaluating the curative effect of microwave ablation for liver cancer were calculated with results of angiography as the golden standard. Results Results of angiography proved that 48 of 73 liver cancer lesions reached complete response after microwave ablation and 25 reached incomplete ablation. The sensitivity, specificity, positive predictive value, negative predictive value, accuracy and Kappa value of MSCT enhanced scan in evaluating the curative effect of microwave ablation for liver cancer were 85.42%, 68.0%, 83.7%, 70.8%, 79.5% and 0.54, respectively, while those of MRI were 91.7%, 92%, 95.7%, 85.2%, 91.8% and 0.82. respectively. The specificity and accuracy of MRI examination were significantly higher than those of MSCT enhanced scan(P〈0.05). Conclusion MSCT enhanced scan and MRI examination can clearly show the changes of liver cancer after microwave ablation. MRI examination is more accurate than MSCT enhanced scan in evaluating the curative effect of microwave ablation for liver cancer.
作者
唐俊
TANG Jun(Department of Intervention Center,Affiliated Zhongshan Hospital of Guangzhou Medical University,Zhongshan 528415,Guangdong Province,China)
出处
《中国CT和MRI杂志》
2018年第7期100-102,108,共4页
Chinese Journal of CT and MRI
关键词
原发性肝癌
多层螺旋CT
磁共振成像
微波消融
疗效
Primary Liver Cancer
Multislice Spiral CT
Magnetic Resonance Imaging
Microwave Ablation
Curative Effect