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安宫牛黄丸加减治疗脑出血急性期脑损伤患者的临床研究 被引量:7

Clinical Study on Modified Angongniuhuang Pill Treatment for Acute Cerebral Injury Patients with Cerebral Hemorrhage
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摘要 目的分析安宫牛黄丸加减治疗脑出血急性期脑损伤患者的临床疗效。方法将90例脑出血急性脑损伤患者根据治疗方法分为两组,对照组44例患者行常规治疗,观察组46例患者基于对照组加用安宫牛黄丸加减治疗,比较两组的治疗效果。结果观察组的治疗总有效率为93.48%,显著高于对照组的77.27%(P<0.05)。治疗后,观察组的NIHSS评分以及hs-CRP、IL-8、BNP水平均显著低于对照组,GCS评分显著高于对照组(P<0.05)。观察组的再出血发生率为2.17%,显著低于对照组的15.91%(P<0.05)。结论安宫牛黄丸加减治疗脑出血急性期脑损伤患者效果显著,再出血发生率低,值得推广。 Objective To analyze the clinical efficacy of modified Angongniuhuang pill treatment for acute cerebral injury patients with cerebral hemorrhage. Methods 90 cases of acute cerebral injury patients with cerebral hemorrhage were divided into the control group (n = 44) and the observation group (n = 46) according to the treatment methods. All cases were given routine therapy; in addition, the observation group was treated with modified Angongniuhuang pill. The curative effects of two groups were compared. Results The total effective rate of the observation group was 93.48%, significantly higher than 11.21 ° % of the control group (P 〈0.05). After treatment, the NIHSS score, and levels of hs-CRP, IL-8 and BNP of the observation group were significantly lower than those of the control group, and the GCS score was significantly higher than that of the control group (P 〈0.05). The incidence of re-hemorrhage of the observation group was 2.17%, significantly lower than 15.91% of the control group (P 〈0.05). Conclusions Modified Angongniuhuang pill treatment for acute cerebral injury patients with cerebral hemorrhage has significant efficacy and low incidence of re- hemorrhage, which is worthy of promotion.
作者 蒋令修 JIANG Lingxiu(Department of Neurology, the First Affiliated Hospital of Henan University, Kaifeng 475000, China)
出处 《临床医学工程》 2018年第6期739-740,共2页 Clinical Medicine & Engineering
基金 国家自然科学基金项目"EMMPRIN在脑出血脑损伤中的作用机制及转化医学研究"(项目编号:8151001181)
关键词 脑出血 急性期脑损伤 安宫牛黄丸加减治疗 Cerebral hemorrhage Acute cerebral injury Modified Angongniuhuang pill treatment
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