摘要
目的采用右佐匹克隆片联合加巴喷丁治疗带状疱疹后遗神经痛的患者,并观察其疗效及安全性。方法对照组60例采用加巴喷丁0.3 tid,维生素B1 10mg tid,甲钴胺片0.5mg tid等药物治疗,观察组60例,在此基础上给予右佐匹克隆片3mg qn,连续2周后改为3mg qon再使用2周,然后评估疗效,并观察治疗过程中的不良反应。结果治疗4周后,观察组与对照组睡眠质量评分比较差异有统计学意义(P<0.05)。观察组痊愈率73.33%,有效率93.33%;对照组痊愈率55.00%,有效率86.67%,两组对比痊愈率比较差异有统计学意义(P<0.05)。结论右佐匹克隆片联合加巴喷丁治疗带状疱疹后遗神经痛会提高患者睡眠质量,促进患者恢复,提高带状疱疹的治愈率,值得推广。
Objective To treat patients with postherpetic neuralgia by right zopicron tablet combined with gabapentin,and to observe the efficacy and safety. Methods In the control group,60 cases were treated with gabapentine 0.3 mg tid,vitamin B1 10mg tid,and methylcobalamin tablet 0.5mg tid,while in the observation group,on this basis,60 cases were treated with right zopicone tablet 3mg qn for 2 weeks,then 3mg qon for 2 weeks,then the curative effect was evaluated and the side effects during the treatment were observed. Results After 4 weeks of treatment,there was a significant difference in sleep quality scores between the observation group and the control group（ P 〈0.05）.In the observation group,the cure rate was 73.33% and the effective rate was 93.33%;In the control group,the cure rate was 55.00%,and the effective rate was 86.67%,and the difference of the cure rate between the two groups was statistically significant（ P 〈0.05）. Conclusion The treatment of postherpetic neuralgia with right zopicron tablet combined with gabapentin can improve the sleep quality,promote the recovery of patients and improve the cure rate of herpes zoster,which is worth popularizing.
作者
黎昌强
廖勇梅
许飏
熊霞
何渊民
Li Changqiang;Liao Yongmei;Xu Yang(The First Affiliated Hospital of Southwest Medical University,Luzhou.Sichuan 646000,Chin)
出处
《四川医学》
CAS
2018年第5期567-569,共3页
Sichuan Medical Journal
