摘要
预防乙型肝炎病毒（hepatitis B virus，HBV）母婴传播是控制慢性HBV感染的关键。我国为之付出了极大努力，也取得了巨大成就。本文介绍了我国预防HBV母婴传播的主要免疫措施和研究进展，总结了对高病毒载量孕妇妊娠晚期口服抗病毒药物预防HBV母婴传播的效果和安全性，并提出了亟待进一步研究的相关问题。
The prevention of mother-to-infant transmission （MTIT） of hepatitis B virus （HBV） plays a critical role in controlling chronic HBV infection. China has put tremendous efforts in preventing MTIT of HBV and now has achieved fruitful results. We briefly introduced the main measures and research advances in immunoprophylaxis against perinatal HBV infection, summarized the efficacy and safety of oral anti-HBV agents, which administered in the third trimester to the gravidas with high viral loads to prevent MTIT of HBV. We also proposed some challenging issues that require further investigation.
作者
周乙华
胡娅莉
Zhou Yihua;Hu Yali(Laboratory of Hepatitis,Nanjing Drum Tower Hospital Nanjing University Medical School Nanjing 210008,China（Zhou YH;Department of Obstetrics and Gynecology,Nanjing Drum Tower Hospital Nanjing University Medical School Nanjing 210008,China)
出处
《中华围产医学杂志》
CAS
CSCD
北大核心
2018年第8期505-509,共5页
Chinese Journal of Perinatal Medicine
关键词
乙型肝炎
传染性疾病传播
垂直
传染病控制
Hepatitis B
Infectious disease transmission
vertical
Communicable disease control
