摘要
白及多糖(Bletillastriata Polysaccharide,BSP)是从传统中药白及提取而得的葡甘聚糖,具有抗炎、抗氧化、抗溃疡、调节机体免疫活性,抗肿瘤等生物活性,有局部滞留性、靶向性、自身降解性、无刺激性、无毒副作用等特性,被广泛应用于食品工业、医药工业和日用化学工业。本文基于BSP的物理和生物特性,重点探讨了白及多糖在创伤敷料及药物载体方面的应用进展,为BSP在医用生物材料方面的开发利用提供参考。
Bletillastriata Polysaccharide（BSP） is glucomannan extracted from traditional Chinese medicine Bletillastriata, which has the effects of anti-inflammatory, anti-oxidation, anti-ulcer and anti-tumor, regulating immune activity, and other biological activity. It has the characteristics of local retention, targeting, self-degradability, non-irritating, non-toxic and non-side effects etc. BSP is widely used in the food industry, pharmaceutical industry and daily chemical industry. This paper focuses on the application of BSP in wound dressings and drug carriers based on the physical and biological characteristics, and provides a reference for the development and utilization of BSP in medical biomaterials.
作者
瞿燕
张晨
廖祯诚
胡铃莉
何瑶
QU Yan;ZHANG Chen;L;HU Ling-li;HE Yao//(School of Pharmary,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,Sichuan)
出处
《中药与临床》
2017年第5期54-58,共5页
Pharmacy and Clinics of Chinese Materia Medica
基金
国家中医药管理局
2014年全国中药特色技术传承人培训项目
四川省科技厅应用基础项目(2015JY0139)
关键词
白及多糖
生物活性材料
创伤敷料
药物载体
Bletillastriata Polysaccharides
bioactive materials
wound dressings
drug carriers
