摘要
目的:研究正常胎儿大脑后动脉(posterior cerebral artery,PCA)两个解剖节段的血流参数随孕周变化规律。方法:用多普勒检测132例正常单胎胎儿PCA两个解剖节段,PCA由基底动脉发出至后交通动脉之前节段(the first segment of posterior cerebral artery,PCAS1)和PCA与后交通动脉汇合之后节段(the second segment of posterior cerebral artery,PCAS2)的速度参数[收缩期峰值流速(peak systolic velocity,PSV)、舒张末期流速(end diastolic velocity,EDV)、时间-平均最大速度(time-average maximum velocity,TAMAXV)、速度时间积分(velocity time integral,VTI)]以及阻力参数[收缩期峰值流速与舒张末期流速比值(systolic peak velocity and end diastolic velocity ratio,S/D)、搏动指数(pulsatility index,PI)、阻力指数(resistance index,RI)]。将PCAS1和PCAS2血流参数分别与孕周行Pearson相关分析及多种曲线拟合,并对比分析两节段间的血流参数差异。结果:PCAS1和PCAS2速度参数随孕周增长而增加(P<0.0001),速度参数与孕周均以Quadratic曲线拟合度最高(P<0.0001)。PCAS1和PCAS2阻力参数与孕周无明显相关性(P>0.05)。PCAS1阻力明显高于PCAS2(P<0.05)。结论:正常胎儿PCA两个节段速度参数均与孕周存在正相关关系,阻力参数与孕周不存在相关关系,两节段存在阻力差异。对正常胎儿PCA血流参数的研究可完善胎儿脑循环的评估,为高危妊娠的监测提供有力的根据及补充。
Objective： To study the blood flow parameters artery （PCA） in normal singleton fetal. for 2 anatomical segments of posterior cerebral Methods： The blood flow velocity parameters peak systolic velocity （PSV）, end diastolic velocity （EDV）, time-average maximum velocity （TAMAXV）, velocity time integral （VTI） and resistance parameters systolic peak velocity and end diastolic velocity ratio （S/D）, pulsatility index （PI）, resistance index （RI） for 2 anatomical segments in PCA were recorded. The first segment of thePCA （PCAS1） was recorded between the origin of PCA and the proximal part of the posterior communicating artery. The second segment of the PCA （PCAS2） was recorded at the distal part of the posterior communicating artery. The blood parameters in both PCAS1 and PCAS2 were analyzed by using Pearson correlation and multiple curves fitting with gestational age （GA）. Paired student＇s t test was performed to compare the difference in blood parameter between PCAS1 and PCAS2. Results： The blood flow velocity parameters in both PCAS1 and PCAS2 were increased with the GA （P〈0.0001）, with the best fitted curves of Quadratic curve （P〈0.0001）. There were no correlations between resistance parameters in PCA and GA （P〉0.05）. Resistance parameters in PCAS1 were higher than those in PCAS2 （P〈0.0S）. Conclusion： The blood flow velocity parameters in both PCAS1 and PCAS2 are increased with GA. The resistance parameters in both PCAS1 and PCAS2 do not change with GA. Study on the velocities and resistance in these 3 arterial branches provides a more comprehensive evaluation on the process of brain circulation.
作者
谭雅
谭宜
周嘉炜
刘玉姗
赵白桦
曾施
TAN Ya;TAN Yi;ZHOU Jiawei;LIU Yushan;ZHAO Baihua;ZENG Shi(Department of Ultrasound,Second Xiangya Hospital,Central South University,Changsha 410011,China)
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2018年第8期886-891,共6页
Journal of Central South University ：Medical Science
基金
国家自然科学基金(81501497)~~
关键词
大脑后动脉
正常胎儿
速度参数
阻力参数
脑循环
posterior cerebral artery
fetus
velocity parameter
resistance parameter
cerebral circulation
