摘要
目的探讨氨氯地平联合厄贝沙坦在2型糖尿病合并高血压老年患者中的疗效及对靶器官的影响。方法将90例高血压合并2型糖尿病老年患者随机分为观察组和对照组,各45例。对照组采用厄贝沙坦治疗,观察组在对照组基础上联用氨氯地平治疗。比较两组的临床效果。结果观察组总有效率明显高于对照组(P<0.05)。观察组的LVEDD、LVESD、E/A、LVEF及6 min步行距离均优于对照组(P<0.05)。观察组的Ccr、ACR、24 h UMALB及BUN水平均优于对照组(P<0.05)。结论 2型糖尿病合并高血压老年患者采用氨氯地平联合厄贝沙坦治疗的临床效果显著,能够显著降低靶器官损害。
Objective To investigate the effects of amlodipine and irbesartan on the efficacy and target organs in elderly patients with type 2 diabetes mellitus and hypertension. Methods Ninety elderly patients with type 2 diabetes mellitus and hypertension were randomly divided into observation group and control group, with 45 cases in each group. The control group accepted irbesartan, and the observation group accepted amlodipine on the basis of the control group. The therapeu-tic effects were compared between the two groups. Results The total effective rate of observation group was significantly higher than that of the control group（P〈0.05）. The LVEDD, LVESD, E/A, LVEF and 6 min walk distance in the observation group were better than those in the control group（P〈0.05）. The Ccr, ACR, BUN and 24 h UMALB levels in the observation group were better than those in the control group（P〈0.05）. Conclusion The clinical efficacy of amlodipine combined with irbesartan in elderly patients with type 2 diabetes mellitus and hypertension is significant, and it can significantly reduce the target organ damage.
作者
李娟
LI Juan(Internal Medicine Department,the Hospital of Lantian County,Xi＇an 710500,China)
出处
《临床医学研究与实践》
2018年第17期40-41,共2页
Clinical Research and Practice
关键词
氨氯地平
厄贝沙坦
2型糖尿病合并高血压
靶器官
amlodipine
irbesartan
type 2 diabetes mellitus and hypertension
target organ
