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腹腔镜与胆道镜辅助胆总管切开取石术对患者炎性指标及生活质量的影响 被引量:1

Laparoscopic and Choledochoscope-assisted Choledocholithotomy in Patients with Inflammatory Markers and Quality of Life
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摘要 目的探讨腹腔镜与胆道镜辅助胆总管切开取石术的临床效果以及对患者炎性指标及生活质量的影响。方法将2015年1月—2016年12月在该院行腹腔镜与胆道镜辅助胆总管切开取石术的56例患者作为观察组,并将同期在该院行开腹手术的56例患者作为对照组,分别对两组患者的临床效果、炎性指标及生活质量进行对比。结果观察组患者的临床效果明显优于对照组患者(t=3.775、4.627、3.052,P<0.05);两组患者术后的炎性指标均明显高于术前,术后1d观察组患者的炎性指标IL-6(35.6±15.6)ng/L、CRP(67.7±16.1)mg/L、PCT(7.8±2.0)μg/L明显高于对照组,差异有统计学意义(t=4.152、3.635、3.198,P<0.05);术后5周观察组患者的生活质量评分(119.2±4.5)分明显高于对照组,差异有统计学意义(t=3.527,P<0.05)。结论腹腔镜与胆道镜辅助胆总管切开取石术治疗胆总管结石的效果显著,值得临床的推广及应用。 Objective This paper tries to investigate the clinical effect of laparoscopic choledochoscope assisted choledocholithotomy and its influence on the inflammatory index and quality of life in patients. Methods From January 2015 to December 2016, 56 patients underwent laparoscopic choledocholithotomy in this hospital as the observation group,and 56 patients underwent laparotomy in this hospital during the same period as control group. The groups were compared on the clinical efficacy, inflammatory index and quality of life. Results The clinical efficacy of the observation group was significantly better than that of the control group(t=3.775, 4.627, 3.052, P〈0.05); the inflammatory index of the two groups was significantly higher than that before the operation, and the inflammation of the observation group was 1 day after the operation. The indexes of IL-6(35.6±15.6)ng/L, CRP(67.7±16.1)mg/L, PCT(7.8±2.0)μg/L were significantly higher than those of the control group, and the difference was statistically significant(t=4.152, 3.635, 3.98,P〈0.05); The quality of life score(119.2±4.5)points was significantly higher in the observation group than in the control group at 5 weeks postoperatively(t=3.527, P〈0.05). Conclusion Laparoscopic and choledochoscope-assisted choledocholithotomy for the treatment of common bile duct stones is effective and worthy of clinical promotion and application.
作者 高元兴 GAO Yuan-xing(Department of General Surgery,Section Two,Qiqihar First Hospital,Qiqihar,Heilongjiang Province,161000 China)
出处 《系统医学》 2018年第8期96-98,共3页 Systems Medicine
关键词 腹腔镜与胆道镜辅助 胆总管切开取石术 炎性指标 生活质量 Laparoscopic and choledochoscope assisted Common bile duct incision Inflammatory markers Quality of life
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