摘要
目的:观察甘草锌颗粒辅助治疗小儿腹泻的临床疗效。方法:收集108例腹泻患儿作为观察对象,按随机数字表法分为观察组与对照组,每组54例。对照组给予蒙脱石散^+微生态制剂治疗,观察组则在对照组的基础上增加甘草锌颗粒辅助治疗,比较观察两组治疗效果。结果:观察组治疗总有效率为96.30%,明显高于对照组的79.63%(P<0.05)。观察组止泻时间为(45.10±5.24)h,明显短于对照组的(51.62±6.05)h(P<0.05)。治疗后,两组免疫功能指标CD3^+、CD4^+、CD4^+/CD8^+水平均明显上调,CD8^+水平明显下调,且观察组CD3^+、CD4^+、CD4^+/CD8^+水平上调幅度、CD8^+水平下调幅度均明显大于对照组(P<0.05)。结论:甘草锌颗粒辅助治疗小儿腹泻疗效显著,可快速缓解腹泻症状,改善免疫功能,有效缩短病程。
Objective： To analyze clinical effects of Licorzine granules in adjuvant treatment of infantile diarrhea. Methods： A total of 108 children with diarrhea were used as the research objects. According to the random number table,these patients were divided into observation group and control group,54 cases in each group. The control group was treated with Montmorillonite powder ^＋ Probiotics,while the observation group was supplemented with Licorzine granules on the basis of the control group. The therapeutic effects were observed and compared between the two groups. Results： The total effective rate in the observation group was 96.30%,which was significantly higher than that in control group of 79.63%（ P〈0.05）. The antidiarrheal duration in the observation group was（ 45.10±5.24） h,which was significantly shorter than that in the control group of（ 51.62±6.05） h（ P〈0.05）. After the treatment,the levels of CD3^＋,CD4^＋and CD4^＋/CD8^＋were significantly up-regulated and the levels of CD8^＋were significantly decreased in both groups. The upregulation of CD3^＋,CD4^＋,CD4^＋/CD8^＋and the downregulation of CD8^＋in the observation group were significantly greater than those in the control group（ P〈0.05）. Conclusions： Licorzine granules are effective for the children with diarrhea. It can relieve the symptoms of diarrhea,improve the immune function and shorten the course of diarrhea.
作者
陈威威
郑婵娟
薛海涛
CHEN Weiwei;ZHENG Chanjuan;XUE Haitao(Jiamusi Central Hospital,Jiamusi Heilongjiang 154002,China)
出处
《中国民康医学》
2018年第12期25-26,29,共3页
Medical Journal of Chinese People’s Health
关键词
甘草锌颗粒
小儿
腹泻
免疫功能
Licorzine granules
Pediatric
Diarrhea
Immune function
