摘要
Background： After the first examination of patients with lymphoma diagnosis, important laboratory tests such as complete blood count; albumin, kidney and liver function tests; uric acid; 132-microglobulin; C-reactive protein （CRP）; erythrocyte sedimentation rate （ESR）; and lactate dehydrogenase （LDH） examinations are recommended. In this study, our aim was to find the relationship between laboratory parameters and the maximum standard uptake value （SUVmax） of positron emission tomography/computed tomography （PET/CT） in patients with lymphoma at the diagnosis and after treatment. Methods： Thirty-tbur lymphoma patients treated at Mustafa Kemal University Internal Medicine Clinic between 2014 and 2017 were included in this retrospective study. Results ofCRP, ESR, LDH, albumin, and white blood cell （WBC） count were recorded betbre each PET scan test, and each parameter was analyzed for correlation with SUV measurements. Results： Spearman＇s correlation test showed that the after-treatment SUV values were significantly correlated with the alter-treatment LDH, ESR, and CRP values （for LDH, ESR, and CRP, R2： 0.453, 0.426, and 0.351; P = 0.007, 0.012, and 0.042, respectively）. On the other hand, albumin and WBC count did not show a significant correlation with the after-treatment SUVmax values （all P 〉 0.05）. Conclusions： CRP, ESR, and LDH values may also be good predictors in patients for whom PET/CT imaging cannot be performed.
Background： After the first examination of patients with lymphoma diagnosis, important laboratory tests such as complete blood count; albumin, kidney and liver function tests; uric acid; 132-microglobulin; C-reactive protein （CRP）; erythrocyte sedimentation rate （ESR）; and lactate dehydrogenase （LDH） examinations are recommended. In this study, our aim was to find the relationship between laboratory parameters and the maximum standard uptake value （SUVmax） of positron emission tomography/computed tomography （PET/CT） in patients with lymphoma at the diagnosis and after treatment. Methods： Thirty-tbur lymphoma patients treated at Mustafa Kemal University Internal Medicine Clinic between 2014 and 2017 were included in this retrospective study. Results ofCRP, ESR, LDH, albumin, and white blood cell （WBC） count were recorded betbre each PET scan test, and each parameter was analyzed for correlation with SUV measurements. Results： Spearman＇s correlation test showed that the after-treatment SUV values were significantly correlated with the alter-treatment LDH, ESR, and CRP values （for LDH, ESR, and CRP, R2： 0.453, 0.426, and 0.351; P = 0.007, 0.012, and 0.042, respectively）. On the other hand, albumin and WBC count did not show a significant correlation with the after-treatment SUVmax values （all P 〉 0.05）. Conclusions： CRP, ESR, and LDH values may also be good predictors in patients for whom PET/CT imaging cannot be performed.
作者
Edip Ucar
Hulya Yalcin
Edip Ucar;Hulya Yalcin;Gamze Hande Kavvasoglu;Gul Ilhan(Department of Internal Medicine, Tayfur Ata Sokmen Medical School, Mustafa Kemal University, Antioch, Hatay 31100, Turkey;Department of Nuclear Medicinel Ta~ur Ata Sokmen Medical School, Mustafa Kemal University, Antioch, HataY 31100, Turkey)
