摘要
目的探讨经改制球囊导管冠脉内注射维拉帕米治疗急性冠脉综合征的效果。方法选取2015年12月~2017年7月我院收治的90例接受经皮冠状动脉介入治疗中发生无复流及慢血流的急性冠脉综合征患者作为研究对象,采用随机数字表法分为对照组和观察组,每组各45例。对照组采用单纯指引导管在冠状动脉内注射维拉帕米,观察组经改制球囊导管冠脉内注射维拉帕米。比较两组的TIMI血流分级及校正TIMI帧数的变化,同时观察患者住院期间不良心血管事件的发生率。结果观察组的TIMI血流分级情况优于对照组,矫正TIMI帧数少于对照组,不良心血管事件发生率(6.67%)少于对照组(31.11%),差异均有统计学意义(P<0.05)。结论经改制球囊导管冠脉内注射维拉帕米治疗无复流及慢血流的急性冠脉综合征具有显著的临床效果,可改善患者冠状血流情况,减少不良心血管事件发生率,保证其自身健康状态,值得临床推广。
Objective To investigate the effect of intracoronary injection of verapamil through restructured balloon catheter in the treatment of acute coronary syndrome（ACS）.Methods A total of 90 ACS patients with no-reflow and slow flow who underwent percutaneous coronary intervention in our hospital from December 2015 to July 2017 were selected as the subjects.They were divided into control group and observation group by random number table method,with 45 cases in each group.In the control group,verapamil was injected into the coronary artery with a simple guiding catheter,and in the observation group,verapamil was injected through restructured balloon catheter.The grading of thrombolysis in myocardial infarction（TIMI） and changes of corrected TIMI frames were compared between the two groups,and the incidence of adverse cardiovascular events during hospital stay was also observed.Results The TIMI flow grading of the observation group was better than that of the control group.The number of corrected TIMI frames was less than that of the control group.The incidence of adverse cardiovascular events in the observation group（6.67%）was lower than that in the control group（31.11%）,the difference was statistically significant（P〈0.05）.Conclusion Treatment of acute coronary syndrome characterized by no-reflow and slow flow with intracoronary injection of verapamil through restructured balloon catheter obtains a remarkable effect on improving coronary blood flow,reducing the occurrence of adverse cardiovascular events,and guaranteeing the own health status,which is worthy of clinical promotion.
作者
文勇军
罗洪春
WEN Yong-jun;LUO Hong-chun(Department of Cardiology,Wugang Zhanhui Hospital in Hu＇nan Province,Wugang 422400,Chin)
出处
《中国当代医药》
2018年第22期79-81,共3页
China Modern Medicine
