摘要
目的:探讨高血压患者P波离散度(Pd)的变化,并研究动态血压各参数与Pd的相关性。方法:选择我院2015年7月至2017年7月收治的100例高血压患者(高血压组),另外选择同期进行健康体检无心血管病的体检者76例作为正常对照组。根据血压昼夜节律,高血压组被进一步分为杓型组(36例)和非杓型组(64例)。所有对象都接受24h动态血压监测和12导联心电图检查,比较各组的P波最大时限(P_(max))、P波最小时限(P_(min))和Pd,分析动态血压参数与Pd的相关性。结果:与正常对照组比较,高血压组P_(max)[(103.13±9.19)ms比(118.04±11.14)ms]和Pd[(24.62±5.96)ms比(38.05±7.76)ms]显著升高,P均=0.001。与杓型组比较,非杓型组P_(max)[(116.04±10.17)ms比(121.13±12.06)ms]和Pd[(35.05±8.01)ms比(40.05±7.16)ms]显著升高,P=0.035,0.002。Pearson相关分析显示,Pd与24h平均收缩压、24h收缩压标准差、24h舒张压标准差、收缩压负荷、白昼平均收缩压、夜间平均收缩压呈显著正相关(r=0.291~0.455,P<0.05或<0.01)。结论:高血压患者收缩压、收缩压负荷及血压标准差与P波离散度存在显著正相关,说明这些指标对评价高血压患者心房损害有更高的价值。
Objective：To explore P wave dispersion（Pd）change in patients with hypertension,and study correlation among ambulatory blood pressure indexes and Pd.Methods：A total of 100 patients with hypertension treated in our hospital from Jul 2015 to Jul 2017 were selected as hypertension group.Another 76 healthy subjects without cardiovascular diseases undergoing physical examination during the same period were selected as normal control group.According to circadian rhythm of blood pressure,hypertension group was further divided into dipper group（n=36）and non-dipper group（n=64）.All subjects received 24 hambulatory blood pressure monitoring and 12-lead ECG.P wave maximum time limit（Pmax）,P wave minimum time limit（Pmin）and Pd were compared among all groups,and correlation among ambulatory blood pressure indexes and Pd were analyzed.Results：Compared with normal control group,there were significant rise in Pmax[（103.13±9.19）ms vs.（118.04±11.14）ms]and Pd [（24.62±5.96）ms vs.（38.05±7.76）ms]in hypertension group,P=0.001 both.Compared with dipper group,there were significant rise in Pmax [（116.04±10.17）ms vs.（121.13±12.06）ms]and Pd [（35.05±8.01）ms vs.（40.05±7.16）ms]in non-dipper group,P=0.035,0.002.Pearson correlation analysis indicated that Pd was significant positively correlated with 24 hmean systolic blood pressure（SBP）,24 hSBP standard deviation（SD）,24 hdiastolic blood pressure SD,SBP load,daytime mean SBP and nighttime mean SBP（r=0.291-0.455,P〈0.05 or〈0.01）.Conclusion：SBP,SBP load and blood pressure SD are significant positively correlated with Pd in patients with hypertension,suggesting that these indexes possess higher value in assessing atrial injury in these patients.
作者
潘华
杜建英
张风雷
李国平
PAN Hua, DU Jian-ying, ZHANG Feng-lei, LI Guo-ping(Department of Special Inspection, People＇s Hospital of Dongying City, Dongying, Shandong, 257091, China)
出处
《心血管康复医学杂志》
CAS
2018年第3期352-354,共3页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
高血压
心电描记术
便携式
血压测定
Hypertension
Electrocardiography
ambulatory
Blood pressure determination
