摘要
目的探讨中晚期肝癌患者实施立体定向放射治疗联合介入治疗的临床效果。方法选择本院及合作单位2014年1月~2017年1月诊治的60例中晚期肝癌患者,按随机数表分组:单纯组(n=30,立体定向放射治疗)、联合组(n=30,立体定向放射治疗联合介入治疗),对比不同方案下患者肿瘤的局部控制率、毒副反应、生活质量、生存期等状况。结果联合组治疗3个月后肿瘤局部控制率、生活质量评分、1年生存率较单纯组明显升高(P<0.05)。两组不良反应发生率比较差异无统计学意义。结论中晚期肝癌患者实施立体定向放射治疗联合介入治疗可达到良好的远近期疗效,并改善患者生活质量。
Objective To investigate the clinical effect of stereotactic radiotherapy combined with interventional therapy in patients with advanced hepatocellular carcinoma. Methods 60 patients with middle and advanced liver cancer treated in our hospital and cooperation unit from January 2014 to January 2017 were divided into two groups： simple group（n=30, stereotactic radiotherapy）, combined group（n=30, stereotactic radiotherapy combined with interventional therapy）, and compared the local control rate and toxicity of the tumor in the different cases. The condition of side effect, quality of life, life period and so on. Results After 3 months of treatment, the local control rate, quality of life score and 1 year survival rate of the combined group were significantly higher than those of the simple group（P0.05）. There was no significant difference in the incidence of side effects between the two groups. Conclusion Stereotactic radiotherapy combined with interventional therapy can achieve good long-term results and improve the quality of life of patients with advanced hepatocellular carcinoma.
作者
吴志瑛
章桂娇
夏婷
Wu Zhiying1, Zhang Guijiao1, Xia Ting 2(1. Nanchang 334 hospital oncology, Nanchang, Jiangxi, 330000, China; 2. Tumor Hospital of PLA 94 hospital, Nanchang, Jiangxi, 330000, China)
出处
《当代医学》
2018年第19期48-50,共3页
Contemporary Medicine
基金
江西省卫生计生委科技计划项目(20154012)
关键词
中晚期肝癌
立体定向放射治疗
介入治疗
临床效果
Advanced liver cancer
Stereotactic radiotherapy
Interventional therapy
Clinical effect
