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中西医联合治疗代偿期乙型肝炎肝硬化的临床研究 被引量:1

Clinical study of combined traditional Chinese and western medicine in the treatment of compensated hepatitis B cirrhosis
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摘要 目的:探讨中西医结合治疗代偿期乙型肝炎肝硬化的临床疗效。方法:收治代偿期乙型肝炎肝硬化患者48例,随机分为对照组和研究组。对照组采用恩替卡韦分散片治疗,研究组在对照组基础上加用柴胡疏肝散治疗,比较两组治疗效果。结果:与治疗前相比,治疗后两组血清丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)水平均显著降低,白蛋白(ALB)水平显著升高(P<0.01);且治疗后研究组血清ALT、AST水平均显著低于对照组(P<0.05),ALB水平较对照组差异无统计学意义(P>0.05)。与治疗前比,研究组肝脏硬度值显著降低(P<0.01),且显著低于对照组(P<0.01)。研究组总有效率显著高于对照组(P<0.01)。结论:中西医联合治疗代偿期乙型肝炎肝硬化能更有效地改善患者肝功能及肝硬化程度,疗效显著,优于常规西医治疗。 Objective:To explore the clinical effect of combined traditional Chinese and western medicine in the treatment of compensated hepatitis B cirrhosis.Methods:48 cases of compensatory hepatitis B cirrhosis were selected.They were randomly divided into control group and study group.The control group was treated with entecavir dispersible tablets,and the study group added Chaihu Shugan powder on the basis of the control group.We compared the treatment effect of the two groups.Results:Compared with those before treatment,serum ALT and AST levels were significantly decreased in two groups after treatment,and serum ALB level was significantly increased(P〈0.01);after treatment,the serum ALT and AST levels in the study group were significantly lower than those in the control group(P〈0.05);the serum ALB level in the study group was not significantly different from that in the control group(P〉0.05).The liver hardness of the study group was significantly lower than that before treatment(P〈0.01),and it was significantly lower than that of the control group(P〈0.01).The total effective rate of the study group was significantly higher than that of the control group(P〈0.01).Conclusion:The combination of traditional Chinese and western medicine in the treatment of compensatory hepatitis B cirrhosis can improve the liver function and the degree of liver cirrhosis more effectively.The curative effect was remarkable,and it was superior to the conventional western medicine.
作者 马玉美 杨峥 段生艳 杨艳 杨定芳 Ma Yumei;Yang Zheng;Duan Shengyan;Yang Yan;Y-ang Dingfang(Baoshan High School of Chinese Medieine(Yunnan)67800)
出处 《中国社区医师》 2018年第18期104-105,共2页 Chinese Community Doctors
基金 保山市科技计划项目(项目编号:2016bs091)~~
关键词 乙型肝炎肝硬化 代偿期 中西医结合 Hepatitis B eirrhosis Compensatort period Combined traditional Chinese and western medicine
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