摘要
目的研究中药川芎对成骨细胞增殖的影响。方法以小鼠成骨细胞株MC3T3-E1为实验对象,以川芎提取液干预作为观察组,以α-MEM培养液干预为对照组。比较两组干预24 h、48 h及72 h的成骨细胞增殖情况(CCK-8值)及ALP活性。结果干预后24 h、48h及72 h观察组的CCK-8值及ALP活性均高于对照组(P<0.05)。结论中药川芎可有效促进成骨细胞的增殖。
Objective To study the influence of traditional Chinese medicine rhizoma chuanxiong on the proliferation of osteoblasts. Methods The osteoblaststrain MC3 T3-E1 of mouse was selected as the experimental subject, and the observation group was respectively intervened with chuanxiong extraction, and the control group was intervened with α-MEM medium. Then the osteoblast proliferation（CCK-8 value） and ALP activity of two groups at 24 h, 48 h and72 h were compared. Results The CCK-8 value and ALP activity of observation group at 24 h, 48 h and 72 h after the intervention were all higher than those of control group（P〈0.05）. Conclusion The traditional Chinese medicine rhizoma chuanxiong can effectively promote the proliferation of osteoblasts.
作者
魏广治
WEI Guangzhi(Department of Stomatology,Nangang Branch of Heilongjiang Provincial Hospital,Harbin Heilongjiang 150001,China)
出处
《中国卫生标准管理》
2018年第11期104-106,共3页
China Health Standard Management
基金
黑龙江省哈尔滨市科技局科技创新后备人才基金(2017RAQXJ235)
关键词
中药川芎
西药
成骨细胞增殖
ALP
药物浓度
骨代谢
traditional chinese medicine rhizoma chuanxiong
western medicine
proliferation of osteoblasts
ALP
drug concentration
bone metabolism
