摘要
目的:探讨使用瑞芬太尼+七氟烷手术麻醉用药后对患者认知功能的影响。方法:收治外科手术患者100例,随机分为对照组与观察组。观察组采用瑞芬太尼+七氟烷联合麻醉用药,对照组采用瑞芬太尼麻醉用药,比较两组麻醉后患者认知功能、苏醒时间、体征。结果:麻醉前及麻醉结束后24 h两组MMSE评分比较,差异无统计学意义(P>0.05);而观察组麻醉结束后6 h、12 h MMSE评分优于对照组(P<0.05);两组图片再认能力对比,差异无统计学意义(P>0.05);麻醉结束后12 h观察组简单计算能力、词语记忆能力优于对照组(P<0.05)。结论:对手术患者使用瑞芬太尼+七氟烷联合麻醉支持,对患者认知功能恢复具有促进作用,可作为临床首选麻醉用药。
Objective：To explore the effect of sevoflurane combined with remifentanil on cognitive function of patients after anesthesia.Methods：100 patients with surgical operation were selected.They were randomly divided into the control group and the observation group.The observation group was given remifentanil combined with sevoflurane anesthesia,and the control group was given remifentanil anesthesia.We compared the cognitive function,the awakening time and the physical signs of the two groups.Results：There was no significant difference in the MMSE scores between groups before anesthesia and in 24 hours after the end of anesthesia（P〉0.05）.At 6 hours and 12 hours of the end of anesthesia,the MMSE score of the observation group was better than that of the control group（P〈0.05）.There was no significant difference in recognition ability between groups（P〉0.05）.After 12 hours of anesthesia,the ability of simple calculation and word memory in the observation group were better than those in the control group（P〈0.05）.Conclusion：Remifentanil combined with sevoflurane anesthesia for patients undergoing surgery can promote cognitive function recovery,and it can be used as the first choice for anesthesia in clinic.
作者
李正时
罗林
Li Zhengshi;Luo Lin(Department of Anesthesiology,the Fourth Hospital of Huangshi City（Hubei）43500)
出处
《中国社区医师》
2018年第19期35-36,共2页
Chinese Community Doctors
关键词
麻醉
瑞芬太尼
七氟烷
认知功能
Anesthesia
Remifentanil
Sevoflurane
Cognitive function
