摘要
从鸡球虫保护性抗原基因的种类、作用机理、免疫效果评价及影响因素等方面对鸡球虫核酸疫苗的研究进展进行了综述,以期为鸡球虫核酸疫苗的研发提供参考。
Coccidiosis is one of the major protozoa in poultry industry. Strong and attenuated live vaccines and drugs are used to control the disease. Nucleic acid vaccines are safe,efficient,stable and easy to prepare.They are widely used for the prevention of chicken coccidiosis. Therefore,the use of chicken coccidia protective antigen genes to construct nucleic acid vaccines has become a research hot spot. In this paper,the current research status,mechanism of action,immune effect evaluation and influencing factors of chicken coccidiosis nucleic acid vaccines are analyzed in order to provide reference for the research and development of chicken coccidiosis nucleic acid vaccines.
作者
闫艳娟
张东林
庞洪泽
常超越
李蕴玉
李佩国
YAN Yanjuan;ZHANG Donglin;PANG Hongze;CHANG Chaoyue;LI Yunyu;LI Peiguo(Hebei Province Key Laboratory of Veterinary Preventive Medicine,Hebei Normal University of Science ＆ Technology,Qinhuangdao Hebei,066600,China)
出处
《河北科技师范学院学报》
CAS
2018年第1期65-69,共5页
Journal of Hebei Normal University of Science & Technology
基金
河北省现代农业产业技术体系蛋鸡产业创新团队岗位项目(项目编号:HBCT2013090203)
2017年河北省硕士研究生创新资助项目(项目编号:CXZZSS2017158)
关键词
鸡球虫
保护性抗原基因
核酸疫苗
研究进展
chicken coccidia
protective antigen gene
nucleic acid vaccine
resesrch progress
