摘要
To the Editor： Benign prostatic hyperplasia （BPH） is a prevalent chronic disease that predominately affects males aged over 40 years, characterized by benign unregulated hyperplasia that arises from stromal and epithelial prostate cells. Although the association between altered microRNA （miRNA） expressions and the incidence of prostate cancer has been widely investigated, there still remains a poor understanding of the mechanism underlying miRNA expressions in BPH of the prostatic stroma. More recently, emerging evidence has highlighted the role ofantitumor miRNA-340 （miR-340） in the event of prostate cancer progression and metastasis.
To the Editor： Benign prostatic hyperplasia （BPH） is a prevalent chronic disease that predominately affects males aged over 40 years, characterized by benign unregulated hyperplasia that arises from stromal and epithelial prostate cells. Although the association between altered microRNA （miRNA） expressions and the incidence of prostate cancer has been widely investigated, there still remains a poor understanding of the mechanism underlying miRNA expressions in BPH of the prostatic stroma. More recently, emerging evidence has highlighted the role ofantitumor miRNA-340 （miR-340） in the event of prostate cancer progression and metastasis.
