摘要
目的:探索糖尿病肾脏病患者火热证候的临床特点及分布规律。方法:采集348例DKD早、中、晚期患者的临床资料,进行火热证候判定,对各火热证候类型的分布及火热证患者的临床表现、理化指标进行分析。结果:(1)本研究中,89.4%的DKD患者均伴有火热证,早、中、晚期伴火热证患者的比例分别为90.5%、89.7%、87.8%。(2)火热证在DKD早期以燥热证最为常见,占61.9%,中期以结热证最为常见,占53.2%,晚期以浊热证最常见,占70%。(3)DKD火热证最常合并气虚证,其次为阳虚证、阴虚证。(4)火热证最常见的临床症状包括口咽干燥、烦躁易怒、大便干结、口苦、口中粘腻、怕热汗出、口中臭秽。(5)在理化指标方面,伴火热证的DKD患者具有较高的尿酸水平。结论:火热证在DKD中分布广泛且贯穿疾病始终,各热邪类型在DKD不同分期的分布具有一定的规律,火热证常与气虚、阳虚、阴虚证并存,其临床表现多样,可能与某些临床理化指标如血尿酸等存在一定的相关关系。
To explore the clinical characteristics and distribution rule of heat syndrome in diabetic kidney dis- ease （DKD） patients. Methods：The clinical materials, clinical symptoms and heat syndrome type were collected, and the distribution of heat syndrome , clinical symptoms and indicators were analyzed. Results： （ 1 ） Patients with heat syndrome accounted for 89.4% of all the patients, and the percentage in the early stage, the middle stage and the advanced stage were 90.5% ,89.7% ,87.8% respec- tively. （2） In the early stage, dryness - heat syndrome is most common seen, heat accumulation syndrome is most frequently seen in the middle stage, accounting for 61.9%, and in the advanced stage, it is damp - heat syndrome that the most common type, accounting for70%. （3）The most common deficiency syndrome of DKD patients with heat syndrome were qi deficiency syndrome,yang deficiency syndrome and yin deficiency syndrome. （4） The symptoms of heat syndrome include oropharyngeal dryness, irritability, dry stool, mouth bitter, mouth sticky, afraid of hot sweating, mouth foul. （5） DKD patients with heat syndrome tend to have a higher level of blood uric acid than those without heat syndrome. Conclusion：The heat syndrome is widely distributed in the DKD and runs through the whole stages. The distribution of the different types of fever in DKD has certain regularity. The heat syndrome is often associated with qi deficiency, yang deficiency and yin deficiency. The clinical manifestation of heat syndrome is diverse. There may be a certain correlation between clinical physical and chemical indicators such as uric acid and heat syndrome.
出处
《中国中西医结合肾病杂志》
2018年第6期489-492,共4页
Chinese Journal of Integrated Traditional and Western Nephrology
基金
北京市科委基金资助项目(No.D131100004713005)
首都卫生发展科研专项资助项目(No.2016-1-14192)
北京中医药大学校级自主基金资助项目(No.2017-JYB-XS-103)
关键词
糖尿病肾脏病
火热证
证候特征
分布规律
Diabetic kidney disease
Heat syndrome
Clinical characteristics
Distribution rule
