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中人氟安植入剂治疗肝癌疗效及安全性分析 被引量:2

Efficacy and safety of human Fluorouracil implants in the treatment of liver cancer
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摘要 目的探讨中人氟安植入剂治疗肝癌疗效及安全性。方法选取自2013年1月至2015年1月行超声引导下肝穿刺瘤内植入中人氟安植入剂的28例肝癌患者为研究对象。比较治疗前后患者卡氏评分、肿瘤大小、肝功能分级情况及治疗后不良反应发生情况,评价有效性及安全性。结果 28例患者中,4例患者因故脱落,24例患者治疗后肿瘤体积减小、卡氏评分增高(P<0.05);治疗前后肝功能分级比较,差异无统计学意义(P>0.05);所有患者均未出现严重不良反应。结论超声引导下肝肿物穿刺植入中人氟安植入剂疗效较好且安全性较高。 Objective To investigate the efficacy and safety of human fluorouracil implant in liver cancer puncture. Methods A retrospective study was performed on 28 cases of patients with liver cancer who were admitted from January 2013 to January2015. Patients were performed liver biopsy under ultrasound-guided within the tumor implanted the fluorine,Karnofsky( KPS) scores,tumor size,liver function grading the occurrence of adverse reactions before and after treatment were compared,and the effectiveness and safety were evaluated. Results Four of the 28 patients fell off for some reason,and 24 cases had reduced tumor volume and increased KPS score( P〈0. 05); comparison of liver function grade before and after treatment showed no significant difference( P〈0. 05); no serious adverse reactions occured. Conclusion The efficacy and safety of human fluorouracil implant in liver tumor puncture guided by ultrasound are better and higher.
作者 李志州 王昊 陈挺松 LI Zhi-zhou;WANG Hao;CHEN Ting-song(Department of General Surgery,The People's Hospital of Xuaneheng City,Xuaneheng 242000,China)
出处 《临床军医杂志》 CAS 2018年第8期911-912,915,共3页 Clinical Journal of Medical Officers
关键词 肝癌 中人氟安植入剂 肝癌穿刺 Liver cancer Fluorouracil implants Liver biopsy
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