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尿激酶注射液联合序贯抗凝疗法治疗老年肺栓塞的临床研究 被引量:1

Urokinase Injection Combined with Sequential Anticoagulation Therapy for Elderly Pulmonary Embolism
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摘要 目的对非高危老年肺栓塞患者通过利用尿激酶注射液与序贯抗凝疗法相结合进行治疗,研究所获得的临床治疗效果。方法随机抽取该院在2015年1月—2017年6月收治的非高危老年肺栓塞患者80例,分成对照组和治疗组,每组40例,将两组患者的总有效率以及不良反应情况进行对比。结果治疗组患者获得的总有效率为92.5%,对照组患者获得的总有效率为72.5%,组间差异有统计学意义(χ~2=15.249 7,P<0.05);治疗组患者不良反应发生率为5.0%,对照组患者不良反应发生率为20.0%,组间差异有统计学意义(P<0.05);治疗组肺部功能恢复消耗时间以及治疗总时间更显著,组间差异有统计学意义(t=8.246 9,10.248 7,P<0.05)。结论老年肺栓塞患者通过使用尿激酶注射液与序贯抗凝疗法相结合的方法展开治疗,显著提高了治疗效果,值得在临床上推广以及应用。 Objective To treat non-high-risk elderly patients with pulmonary embolism by using urokinase injection combined with sequential anticoagulant therapy to study the clinical treatment effect. Methods A total of 80 non-highrisk aged pulmonary embolism patients admitted to the hospital from January 2015 to June 2017 were randomly divided into control group and treatment group with 40 cases in each group. Reactions were compared. Results The total effective rate was 92.5% in the treatment group and 72.5% in the control group. There was a significant difference between the two groups(χ^2=15.249 7,P〈0.05); Adverse reactions in the treatment group was 5.0%. The incidence of adverse reactions in the control group was 20.0%. There was a significant difference between the two groups(P〈0.05). The time spent on pulmonary function recovery and the total treatment time were more significant in the treatment group, being statistically significant(t =8.246 9, 10.248 7,P〈0.05). Conclusion Elderly patients with pulmonary embolism were treated with a combination of urokinase injection and sequential anticoagulant therapy. The treatment effect was significantly improved and it is worthy of promotion and application in clinical practice.
作者 黎劲松 LI Jin-song(Department of Pulmonary Disease, Section One, Chinese Medicine Hospital of Jiangjin, Chongqing, 402260 Chin)
出处 《系统医学》 2018年第12期49-50,59,共3页 Systems Medicine
关键词 老年患者 肺栓塞 尿激酶注射液 序贯抗凝疗法 临床效果 Elderly patients Pulmonary embolism Urokinase injection Sequential anticoagulant therapy Clinical effect
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