5Ntisslein-Volhard C, Wieschaus E. Mutations affecting seg- ment number and polarity in Drosophila [-J]. Nature, 1980, 287(5785) ; 795-801.
6Ogden SK, Ascano M Jr, Stegman MA, et al. Regulation of Hedgehog signaling: a complex story [J]. Biochem Pharma- col, 2004, 67(5) : 805-14.
7Xie J, Bartels CM, Barton SW, et al. Targeting hedgehog signaling in cancer research and clinical developments [-J]. Onco Targets Ther, 2013, 6: 1425-35.
8Mohan SV, Chang AL. Precision medicine and precision therapeuties: hedgehog signaling pathway, basal ceil carcino- ma and beyond [-J]. Semin Cutan Med Surg, 2014, 33(2) : 68-71.
9Sun GW Tang EY, Yang XD, et al. Salvage treatment for recurrent oral squamous cell carcinoma [J]. J Craniofac Surg, 2009, 20(4) : 1093-6.
10van den Brink GR. Hedgehog signaling in development and homeostasis of the gastrointestinal tract [J]. Physiol Rev, 2007, 87(4) : 1343-75.