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临床药师对抗菌药物使用强度指标的干预研究 被引量:8

Effect of clinical pharmacist intervention on antibacterial use density in inpatients
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摘要 目的评估临床药师干预对抗菌药物使用强度的影响。方法临床药师对我院抗菌药物使用强度超标进行问题分析、找出原因、确定目标、制定并实施干预措施。对干预前2017年1月—3月与干预后2017年4月—12月的抗菌药物使用强度进行比较。结果临床药师干预前后,全院及重点外科科室(不合理使用率前5位科室)抗菌药物使用率并无明显下降,但全院及重点外科科室的抗菌药物使用强度明显降低(50.4 vs 31.1 DDDs,86.5 vs 48.1 DDDs,P<0.05),全院抗菌药物使用强度达标(31.1 DDDs,<40 DDDs)。重点外科科室抗菌药物不合理使用率明显下降(56.7%vs 31.3%,P<0.05)。结论临床药师实施有效干预方案,可明显提高重点外科科室抗菌药物合理使用率,降低住院患者抗菌药物使用强度,故临床药师干预是住院患者抗菌药物使用强度降低的重要推力。 Objective To assess the influence of clinical pharmacist intervention on antibacterial use density in inpatients. Methods Clinical pharmacist analyze problem and reason,set goal,draft and implement measures since antibacterial use density exceeded the standards(40 DDDs).We compared antibacterial use density in inpatients before(from January 2017 to March 2017)and after(from April 2017 to December 2017)clinical pharmacist intervention.Results After clinical pharmacist intervention,antibacterial use rates for whole hospital and key surgical departments(The top five departments in the irrational use rates of antibacterial drugs)did not change,but antibacterial use density for whole hospital and key surgical departments markedly decreased(50.4 vs 31.1 DDDs,86.5 vs 48.1 DDDs,P<0.05),therefore antibacterial use density in inpatients conformed to control standards(31.1 DDDs,<40 DDDs).Irrational use rates of antibacterial drugs for key surgical departments significantly decreased(56.7% vs 31.3%,P<0.05).Conclusions Clinical pharmacist implement effective interventive measures to improve rational use of antibacterial drugs in key surgical departments and reduce antibacterial use density in inpatients,then clinical pharmacist intervention is the important power for the reduction of antibacterial use density in inpatients.
机构地区 乐山市人民医院
出处 《基层医学论坛》 2018年第28期4042-4044,共3页 The Medical Forum
关键词 抗菌药物 使用强度 临床药师 干预效果 Antibacterial agents Use density Clinical pharmacist Intervention effect
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