摘要
目的探讨氟喹诺酮类药物在临床应用中的不良反应以及用药原则。方法选取本院2016年2月~2017年3月使用氟喹诺酮类药物出现不良反应的70例患者,分析所有患者使用的药品种类以及不良反应发生情况。结果在所有氟喹诺酮类药物使用中,不良反应发生率最高的药物为环丙沙星,占41.18%;其次为加替沙星,占29.41%;而在不良反应发生情况中,胃肠系统不良反应发生率最高,占50.94%;其次为皮肤,占45.59%。结论在使用氟喹诺酮类药物的过程中,需要注重药物的不良反应,根据患者的实际情况选择合适的药物,以此来降低不良反应的发生率。
Objective To investigate the adverse reactions and principles of drug use fluoroquinolones in clinical application. Methods From February 2016 to March 2017,70 patients with adverse reactions of fluoroquinolones were selected and the types of drugs used and the occurrence of adverse reactions were analyzed.Results In the use of all fluoroquinolones,ciprofloxacin was the highest rate of adverse drug reactions accounting for 41.18%,followed by gatifloxacin,accounting for 29.41%.The incidence of adverse reactions in gastrointestinal system was the highest accounting for 50.94%,followed by skin accounting for 45.59%. Conclusion In the course of using fluoroquinolones,we should pay attention to the adverse reactions of the drugs and choose the appropriate drugs according to the actual situation of the patients,so as to reduce the incidence of adverse reactions.
作者
沈孟杰
SHEN Meng-jie(Department of Pharmacy,Tianjin Third Central Hospital Branch,Tianjin 300250,China)
出处
《医学信息》
2018年第15期135-136,共2页
Journal of Medical Information
关键词
氟喹诺酮类药物
不良反应
用药原则
Fluoroquinolones
Adverse reactions
Principles of drug use
