摘要
目的研究固肾清浊汤联合西医治疗慢性阻塞性肺疾病(COPD)稳定期患者的临床疗效及对患者肺功能、睡眠质量的改善作用。方法选取本院2016年1月至2018年1月收治的98例COPD稳定期患者作为研究对象,将其随机分为对照组与观察组,各49例。对照组采取常规西医西药治疗,观察组在对照组的基础上联合应用自拟固肾清浊汤治疗。治疗3个月后,评估两组临床疗效,观察两组患者治疗前、后的肺功能指标、活动耐力指标及睡眠质量情况。结果观察组治疗总有效率为95.92%,高于对照组的83.67%(P<0.05)。治疗后,两组FEV1、PEF、FEV1/FVC、FVC与6MWT均较治疗前明显改善,且观察组优于对照组(P<0.05)。治疗后,两组PSQI量表各维度及PSQI总分均降低,且观察组低于对照组(P<0.05)。结论固肾清浊汤联合常规西医治疗COPD稳定期患者疗效理想,可有效改善患者的肺功能、活动耐力、睡眠质量,从而全面提高患者的生活质量。
Objective To study the clinical efficacy of Gushen Qingzhuo decoction combined with western medicine in the treatment of patients with chronic obstructive pulmonary disease（COPD） at stable phase and its role on the lung function and sleep quality of patients. Methods Ninety-eight patients with stable COPD admitted in our hospital from January 2016 to January 2018 were enrolled in the study and randomly divided into control group and observation group,with 49 cases in each group. The control group was treated with conventional western medicine, and the observation group was treated with the self-made Gushen Qingzhuo decoction on the basis of the control group. After 3 months of treatment,the clinical efficacy of the two groups was evaluated. The lung function indexes, activity endurance indexes and sleep quality before and after treatment of the two groups were observed. Results The total effective rate of treatment in the observation group was 95.92%, which was higher than 83.67% in the control group（P〈0.05）. After treatment, the FEV1,PEF, FEV1/FVC, FVC and 6 MWT of the two groups significantly improved compared with those before treatment, and those of the observation group were better than the control group（P〈0.05）. After treatment, the scores for each dimension of PSQI scale and PSQI total scores of the two groups decreased, and those the observation group were lower than the control group（P〈0.05）. Conclusion Gushen Qingzhuo decoction combined with conventional western medicine in the treatment of patients with COPD at stable phase is effective, which can effectively improve the lung function, activity endurance and sleep quality of patients, so as to improve the overall quality of life of patients.
作者
王萍
高永宏
陈广峰
WANG Ping, GAO Yong-hong, CHEN Guang-feng(Respiratory Medicine Department, Xi＇an Aerospace General Hospital, Xi＇an 710100, China)
出处
《临床医学研究与实践》
2018年第24期104-106,共3页
Clinical Research and Practice
关键词
稳定期慢性阻塞性肺疾病
肺功能
睡眠质量
固肾清浊汤
chronic obstructive pulmonary disease at stale phase
lung function
sleep quality
Gushen Qingzhuo decoction
