摘要
目的探讨阻塞性睡眠呼吸暂停综合征(OSAS)对冠心病(CHD)患者心脏的心肌缺血总负荷(TIB)以及Gensini评分影响的研究。方法选取2015年6月~2017年6月在青岛市中心医院接受治疗的120例CHD合并OSAS患者,根据OSAS病情程度不同将患者分为CHD合并轻度OSAS组(A组,35例)、CHD合并中度OSAS组(B组,57例)及CHD合并重度OSAS组(C组,28例),对所有患者入院后血浆髓过氧化物酶(MPO)、高敏C反应蛋白(hs-CRP)及三酰甘油(TG)水平予以测定。结果OSAS病情越严重,CHD患者MPO、同型半胱氨酸(Hcy)、甲状腺球蛋白(TG)等指标越高,差异存在统计学意义(P<0.05);3组患者TIB以及Gensini评分差异有统计学意义(P<0.05),且病情越严重,TIB、Gensini评分越高。结论 OSAS病情严重程度与冠心病患者心脏病情相关,OSAS病情越严重,CHD患者MPO、Hcy、TG等指标越高,应给予高度关注。
Objective To explore the correlation between obstructive sleep apnea syndrome（OSAS） and coronary heart disease（CHD） patients with adverse cardiac events and prognosis. Methods The research subject is 120 patients of CHD with OSAS treated in our hospital from June 2015 to June 2017. Based on different degree of OSAS illness, subjects were divided into CHD with mild OSAS group（group A,35 cases） merge moderate OSAS and CHD group（group B,57 cases） and CHD with severe OSAS group（group C,28 cases）,of all patients admitted to hospital after plasma myeloperoxidase（MPO）, high-sensitivity c-reactive protein（hs-CRP） and three acyl glycerin（TG） level shall determine. Results The higher the severity of OSAS,the higher the indexes of MPO,Hcy and TG in patients with CHD,the difference was statistically significant（P〈 0.05）. There were statistically significant differences in the total myocardial ischemia（TIB） and Gensini scores in the three groups（P〈 0.05）. Conclusion the severity of OSAS is closely related to the adverse events and prognosis of patients with coronary heart disease.
作者
王丽丽
于瀚宇
黄晓
徐德祥
Wang Lili;Yu Hanyu;Huang Xiao(Department of Respiratory Medicine,Central Hospital of Qingdao,Qingdao 266042,China)
出处
《中华保健医学杂志》
2018年第4期324-326,共3页
Chinese Journal of Health Care and Medicine
关键词
阻塞性睡眠呼吸暂停综合征
冠心病
预后
相关性
Obstructive sleep apnea syndrome
Coronary heart disease
Prognosis
Correlation
