摘要
目的:观察妊娠期糖尿病患者脐动脉血流参数及对妊娠结局的影响。方法:2015年12月—2017年2月本院行产检并确诊的妊娠期糖尿病患者120例(观察组)及同期健康妊娠女性120例(对照组)为研究对象,检测两组孕18~20周时脐动脉血流相关参数(PI、RI和S/D),观察妊娠结局,统计分析脐动脉血流参数与妊娠期糖尿病患者不良妊娠结局的相关性。结果:脐动脉血流PI、RI和S/D观察组高于对照组(P<0.05);观察组脐动脉血流参数异常升高者不良妊娠结局发生率、剖宫产率高于脐动脉血流正常者(79.7%比21.7%)(χ~2=39.036,P=0.000)、(66.2%比26.1%)(χ~2=18.277,P=0.000),新生儿低血糖、产褥期感染和产后出血等不良分娩结局发生率高于脐动脉血流正常者(16.2%比8.7%)(χ~2=5.791,P=0.016<0.05);脐动脉血流PI、RI和S/D值均与妊娠不良结局的发生呈正相关性(r=0.903、0.775、0.826;P=0.000、0.016、0.004)。结论:妊娠期糖尿病患者孕18~20周脐动脉血流PI、RI和S/D较健康妊娠女性增大,且与妊娠不良结局发生呈正相关,该检测对妊娠期糖尿病的发生和妊娠不良结局具有一定的预测价值,妇科临床应予以重视。
Objective：To observe the influence of changes of umbilical artery blood flow parameters on pregnancy outcomes of pregnant women with gestational diabetes mellitus（GDM）.Methods：120 pregnant women with GDM who had accepted antenatal examination and had confirmed the diagnosis of GDM in Yuhuan people＇s hospital of Zhejiang province were selected in observation group,and another 120 healthy pregnant women at the same time were in control group from December 2015 to February 2017.The umbilical artery blood flow related parameters（PI,RI and S/D）of all pregnant women were measured at 18-20 gestational weeks,and the pregnancy outcomes were observed in both groups,and the correlation between the umbilical artery blood flow parameters and the adverse pregnancy outcomes of pregnant women with GDM was analyzed.Results：The value of PI,RI and S/D of women in observation group were significant higher than those of women in control group（P〈0.05）.The incidence of adverse pregnancy outcomes and the rate of cesarean section of women with abnormal umbilical artery blood flow parameters were significant higher than those with normal umbilical artery（79.7% vs.21.7%,χ^2=39.036,P=0.000）and（66.2% vs 26.1%,χ^2=18.277,P =0.000）.The incidence of neonatal hypoglycemia,puerperium infection and postpartum hemorrhage of women with abnormal umbilical artery blood flow parameters were significant higher than those with normal umbilical artery blood flow（16.2% vs 8.7%,χ^2=5.79,P=0.016）.The umbilical artery blood flow PI,RI and S/D were positively correlated with the incidence of adverse pregnancy outcomes（r=0.90,0.78,0.83;P=0.000,0.016,0.004）.Conclusion：At 18-20 gestational weeks,the umbilical artery blood flow PI,RI and S/D of pregnant women with GDM are higher than those of healthy pregnant women,which have positive correlation with the adverse pregnancy outcomes.These indexes maybe have predictive value on the occurrence of GDM and the adverse pregnancy outcomes,so they should be paid more attention to in obstetrics clinical.
作者
吕莹
LV Ying(Yuhuan People＇s Hospital of Zhej iang Province,Zhejiang,317600)
出处
《中国计划生育学杂志》
2018年第8期679-682,共4页
Chinese Journal of Family Planning
关键词
妊娠期糖尿病
脐动脉血流
妊娠结局
Gestational diabetes mellitus
Umbilical artery blood flow
Pregnancy outcomes
