摘要
目的观察毫火针结合308nm准分子光治疗白癜风临床疗效。方法选取62例白癜风患者,每例患者选取2处相邻或者对称位置的白斑,并随机分入A,B组,A组给予308准分子光照射治疗(2次/周)基础上加用火针治疗(1次/周);B组只采用308准分子光照射(方法同A组)。分别于治疗4周、8周和12周后进行疗效评价及治疗12周后不良反应分析。结果 A组4周、8周和12周有效率为37.1%,53.2%和70.1%,B组有效率为27.4%,43.5%和58.1%,治疗12周后,A组疗效高于B组,差异有统计学意义(P<0.05);两组患者不同部位的疗效比较,A组四肢、手足效果高于B组,差异有统计学意义(P<0.05)。两组患者不良反应轻微,无明显差异(P>0.05)。结论毫火针联合308nm准分子光治疗白癜风疗效好,安全经济,更适用于四肢、手足部位。
Objective To compare clinical efficacy of milli-fire needle combined with 308 nm excimer light and simple 308 nm excimer laser in the treatment of vitiligo. Methods Sixty-two cases of vitiligo patients were selected,2 symmetric or adjacent white of each patient was selected and randomly divided into A and B group. A group received 308 excimer laser irradiation therapy（2 times/week） based on the use of milli-fire needle treatment（1 times/week）; B group with 308 excimer laser radiation therapy（2 times/week）. After 4,8 and 12 weeks of treatment,the efficacy evaluation and adverse reaction were analyzed. Results At 4 weeks,8 weeks and 12 weeks efficiency of A group was 37. 1%,53. 2% and 70. 1%,B group was 27. 4%,43. 5% and 58. 1%,after 12 weeks of treatment,the overall efficacy of A group was significantly higher than that in B group,the difference was statistically significant（P 〈0.05）; The curative effect of different parts of the2 groups was compared,the effect of extremities and hand feet in group A was higher than that in group B（P 〈0.05）. No serious adverse reaction occurred in all 2 groups. Conclusion It is safe and economical to treat vitiligo with needle and 308 nm excimer light. It is more suitable for extremities,hands and feet.
作者
李惠
陶书杰
赵学良
金小力
LI Hui;TAO Shujie;ZHAO Xueliang;JIN Xiaoli(Department of Dermtology Weifang Medical University,weifang 261042,China;Department of Dermatology,Weifang People＇s Hospital)
出处
《潍坊医学院学报》
2018年第3期211-213,共3页
Acta Academiae Medicinae Weifang
