摘要
目的研究术前预防应用抗感染药物及综合措施对降低妇产科围手术期感染的疗效。方法选取2015年9月-2017年8月医院妇产科围手术期患者148例,采用随机数字表法,将患者分为试验组和对照组,各74例。对照组采用术后抗感染药物及常规治疗方法,试验组采用术前预防抗感染药物及综合性治疗措施,观察比较两组患者术前和术后的生命体征、C-反应蛋白、降钙素原水平,术后切口愈合等级、感染率及平均住院时间、住院费用等情况。结果试验组患者痊愈65例占87.84%,对照组患者痊愈42例占56.76%,试验组患者手术疗效优于对照组患者(Z=4.851,P=0.012);术后3d,试验组患者C-反应蛋白、降钙素原水平分别为(2.63±0.70)mg/L、(2.80±0.83)ng/mL,均低于对照组患者(P<0.05);试验组患者术后体温、体温恢复时间、住院时间及住院费用均少于对照组患者(P<0.05)。结论术前预防应用抗感染药物联合综合措施利于降低妇产科围手术期感染率,为妇产科围手术期感染防控提供了理论依据和数据支持。
OBJECTIVE To investigate the effect of preoperative prevention of anti-infective drugs and comprehensive measures on reducing perioperative infections in obstetrics and gynecology.METHODS A total of 148 patients with perioperative obstetrics and gynecology from Sep.2015 to Aug.2017 were selected,and were randomly divided into observation group and control group,with 74 cases in each group.The control group was treated with anti-infective drugs and routine treatment.The observation group was treated with preoperative anti-infective drugs and comprehensive treatment measures.The preoperative and postoperative vital signs,levels of C-reactive protein and procalcitonin,postoperative incision healing grade,infection rate,and the average length of stay and hospital costs between the two groups were observed and compared.RESULTS Totally 65 patients in the observation group were cured,accounting for 87.84%,42 cases in the control group were cured,accounting for 56.76%,and the curative effect of the patients in the observation group was significantly better than that in the control group（Z=4.851,P=0.012）.After 3 dof treatment,the levels of C-reactive protein and calcitonin in the observation group were（2.63±0.70）mg/L and（2.80±0.83）ng/mL,which were significantly lower than those in the control group（P〈0.05）.The body temperature,the body temperature recovery time,the average hospitalization time and the cost of the patients in the observation group were significantly less than those in the control group（P〈0.05）.CONCLUSIONPreoperative prophylaxis of anti-infective drugs combined with comprehensive measures is helpful to reduce the perioperative infection rate of obstetrics and gynecology,which provides the theoretical basis and data support for perioperative infection prevention and control of obstetrics and gynecology.
作者
高虹
邹科
张广敏
周新欢
徐小晶
雷雯
GAO Hong;ZOU Ke;ZHANG Guang-min;ZHOU Xin-huan;XU Xiao-jing;LEI Wen(Nanyang Central Hospital,Nanyang,Henan 473000,China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2018年第15期2365-2368,共4页
Chinese Journal of Nosocomiology
基金
河南省医学科技攻关计划基金资助项目(201512341)
关键词
感染
妇产科
围手术期
术前
疗效
Infection
Obstetrics and gynecology
Perioperative period
Preoperative
Efficacy
