摘要
淋巴细胞亚群是评估免疫系统不可或缺的实验室指标,流式细胞术分析外周血淋巴细胞亚群在临床各类疾病中的应用日益广泛,但是在不同类型和不同年龄阶段的新生儿的感染性疾病的临床诊断、病情变化、评估疾病预后方面的实际应用,目前仍缺乏统一的认识.新生儿感染性疾病是造成新生儿死亡的主要原因之一.目前临床上常用的白细胞、降钙素原、C反应蛋白等炎症指标并不敏感,且无明显特异性,血培养阳性率低,培养时间较长,培养结果可能受到抗生素的应用及标本污染的影响,故寻找适合不同类型及不同年龄段新生儿的感染性疾病的早期诊断、病情变化及预后评估的可靠的实验室指标,具有非常重要的意义.
Lymphocyte subsets is an indispensable laboratory index to evaluate the immune system. Flow cytometry analysis of peripheral blood lymphocyte subsets has been widely used in clinical diseases. However, there is still a lack of unified understanding of clinical diagnosis and evaluation of the disease severity and prognosis in different types and different stages of neonatal infectious disease. Neonatal infectious disease is one of the main causes of neonatal death. The commonly used inflammatory indexes such as white blood cells, procalcitonin, C-reactive protein are not sensitive and have no obvious specificity. The positive rate of blood culture is low and the culture time is long, the result of culture may be contaminated by antibiotics and specimen. So looking for specific laboratory examinations to early diagnose and evaluate the severity and prognosis for different types and different ages of neonatal infectious disease is very important.
作者
杨慧云
YANG Hui-yun(Children＇s Hospital Affiliated to Soochow University,Suzhou,Jiangsu,2 15003,China)
出处
《中国血液流变学杂志》
CAS
2018年第1期122-125,共4页
Chinese Journal of Hemorheology
关键词
外周血淋巴细胞亚群
新生儿感染
流式细胞仪
peripheral blood lymphocyte subsets
neonatal infection
flow cytometry
