摘要
目的采用黛力新联合三联疗法治疗消化性溃疡的临床价值。方法方便选取2016年10月—2017年10月收治的120例消化性溃疡患者为研究对象,划分成两组,每组60例,对常规组患者实施三联疗法治疗,对实验组患者实施黛力新和三联疗法的联合治疗,对比两组的治疗总有效率和不良反应发生率、抑郁评分和Hp根除率以及溃疡复发率。结果经过治疗后,常规组治疗总有效率为71.7%,实验组治疗总有效率为93.3%。比较两组的治疗总有效率,差异有统计学意义(χ2=9.75,P<0.05);常规组Hp根除率为70.0%,实验组Hp根除率为91.7%。两组间比较差异有统计学意义(χ2=9.09,P<0.05)。此外,实验组患者的抑郁评分明显要低于常规组,比较两组,差异有统计学意义(t=11.645,P<0.05);常规组消化性溃疡复发率为23.3%,实验组消化性溃疡复发率为5.0%。对比差异有统计学意义(χ2=8.29,P<0.05)。常规组不良反应发生率为11.7%,实验组不良反应发生率为10.0%,两组间对比不良反应发生率,差异无统计学意义(χ2=0.768,P>0.05)。结论在消化性溃疡的治疗中,采用黛力新和三联疗法的联合治疗方法 ,疗效确切,临床价值极高,可广泛地在临床上推广。
Objective To evaluate the clinical value of Pulixin combined with triple therapy in the treatment of peptic ulcer.Methods 120 patients with peptic ulcer who were admitted from October 2016 to October 2017 were convenient selected as the study subjects. They were divided into two groups, 60 in each group. Triad therapy was performed on the routine group and the patients in the experimental group were treated with force. The combined treatment of new and triple therapy compared the total effective rate of treatment and incidence of adverse reactions, depression score and Hp eradication rate, and ulcer recurrence rate between the two groups. Results After treatment, the total effective rate in the conventional group was71.7%, and the total effective rate in the experimental group was 93.3%. The total effective rate of treatment in the two groups was compared, the difference was statistically significant（χ^2=9.75, P〈0.05）; conventional groupHp eradication rate was 70.0%, experimental groupHp eradication rate was 91.7%. The difference between the two groups was statistically significnat（χ^2=0.09, P〈0.05）. In addition, the depression score of the experimental group was significantly lower than that of the conventional group. The comparison between the two groups was between the groups the difference was statistically signficant（t=11.645, P〈0.05）; the recurrence rate of the peptic ulcer in the conventional group was 23.3%. The peptic ulcer recurred in the experimental group was 5.0%. the difference was statistically significant（χ^2=8.29, P〈0.05）. In addition, the incidence of adverse reactions in the conventional group was 11.7%, and the incidence of adverse reactions in the experimental group was 10.0%. There was no significant difference in the incidence of adverse reactions between the two groups（χ^2=0.768, P〉0.05）. Conclusion In the treatment of peptic ulcers, the combination therapy with Pelixin and triple therapy has a definite curative effect and a high clinical value, and can be widely used in clinical practice.
作者
丁维岭
DING Wei-ling(Department of Gastroenterology,Dong＇a County People＇s Hospital,Liaocheng,Shandong Province,252004 China)
出处
《中外医疗》
2018年第21期16-18,24,共4页
China & Foreign Medical Treatment
关键词
黛力新联合
三联疗法
消化性溃疡
临床价值
Pelvic syndrome combined
Triple therapy
Peptic ulcer
Clinical value
