摘要
目的探讨七味白术散合补阳还五汤加减治疗肥胖2型糖尿病的临床疗效,分析患者血糖、胰岛素抵抗改善效果。方法将2016年1月—2017年10月入院行肥胖2型糖尿病(中医:消渴-脾虚湿盛、痰瘀内阻)治疗的265例患者作为本次观察对象,随机分为两组,其中对照组132例(常规治疗)、观察组133例(加七味白术散合补阳还五汤),比较空腹胰岛素(FINS)、体质指数(BMI)、空腹血糖(FBG)、餐后2小时血糖(2 h PBG)、胰岛素敏感指数(ISI)治疗前后差异。结果治疗后观察组空腹血糖(FBG)、餐后2小时血糖(2 h PBG)、BMI及空腹胰岛素(FINS)水平低于对照组,P<0.05,胰岛素敏感性指数(ISI)较对照组明显改善,P<0.05。结论临床对肥胖2型糖尿病者联合七味白术散合补阳还五汤治疗,患者血糖、胰岛素分泌、体质指数可进一步改善。
Objective To investigate the effect of Qiwei Baizhu Powder and Buyang Huanwu Decoction on obese type 2 diabetes mellitus, and to analyze the improvement effect of blood glucose and insulin resistance. Methods From January 2016 to October 2017, 265 cases of obese type 2 diabetes mellitus（TCM Syndrome Type： spleen deficiency dampness and phlegm stasis） were randomly divided into two groups, of which 132 cases in the control group（conventional treatment） and 133 cases in the observation group（Qiwei Baizhu Powder and Buyang Huanwu Decoction）. The differences in two groups of fasting insulin（FINS）, body mass index（BMI）, fasting blood glucose（FBG）, postprandial 2 hour blood glucose（2 h PBG）, and insulin sensitivity index（ISI） were compared. Results The levels of fasting blood glucose（FBG）, 2 hours postprandial blood glucose（2 h PBG）, BMI and fasting insulin（FINS） were significantly lower than those in the control group（P 〈 0.05）, and the insulin sensitivity index（ISI） was significantly improved（P 〈 0.05） compared with the control group. Conclusion Combined application of Qiwei Baizhu Powder and Buyang Huanwu Decoction in the treatment of obese type 2 diabetes mellitus can further improve blood glucose, insulin secretion, body mass index.
作者
王全兴
郑晓军
白雅彬
WANG Quanxing;ZHENG Xiaojun;BAI Yabin(Department of Endocrinology,Quanzhou Hospital of Traditional Chinese Medicine,Quanzhou Fujian 362000,China)
出处
《中国卫生标准管理》
2018年第17期105-107,共3页
China Health Standard Management
关键词
胰岛素抵抗
2型糖尿病
肥胖
七味白术散
补阳还五汤
疗效
insulin resistance
type 2 diabetes
obesity
Qiwei Baizhu Powder
Buyang Huanwu decoction
clinical efficacy
