摘要
Objective： To observe the effect of electroacupuncture （EA） at Jiaji （EX-B 2） points plus hydro-acupuncture with sinomenine hydrochloride for low back pain caused by compression fractures in the elderly. Methods： Ninety-five elderly in-patients with low back pain caused by compression fractures were randomly divided into an observation group and an EA group according to the visit sequence. Both groups received the same basic treatment. In the EA group, 48 cases were treated with EA at Jiaji （EX-B 2） points plus the basic therapy; 47 cases in the observation group received the basic treatment plus EA and hydro-acupuncture with sinomenine hydrochloride at Jiaji （EX-B 2） points. The levels of osteoprotegerin （OPG） and interleukin-1β（IL-1β） in peripheral blood were measured by enzyme-linked immunosorbent assay （ELISA） before and at the 21st day of treatment in both groups. Oswestry disability index （ODI） and visual analog scale （VAS） scores were used to analyze the clinical efficacy. Results： After treatment, the OPG content in the observation group was higher with statistical significance compared with that before treatment in the observation group and after the treatment in the EA group, respectively （both P〈0.05）; the content of IL-1β, ODI and VAS scores were lower than those before treatment in the observation group and after treatment in the EA group with statistical significances （all P〈0.05）. Conclusion： The combination of EA and hydro-acupuncture with sinomenine hydrochloride at Jiaji （EX-B 2） points is effective for low back pain caused by compression fractures in the elderly, and is superior to EA at Jiaji （EX-B 2） points alone.
目的：观察电针夹脊穴结合穴位注射盐酸青藤碱注射液治疗老年椎体压缩性骨折腰痛的临床疗效。方法：将纳入的95例老年椎体压缩性骨折腰痛住院患者按入院顺序随机分为观察组和电针组。两组患者均接受相同的基础治疗，电针组48例在基础治疗基础上加用电针夹脊穴治疗；观察组47例在接受与电针组相同的基础治疗和电针夹脊穴治疗基础上加用夹脊穴注射盐酸青藤碱注射液治疗。两组均于治疗前和治疗第21天时采用酶联免疫吸附（ELISA）检测外周血骨保护素（OPG）和白介素-1β（IL-1β）的含量，采用Oswestry功能障碍指数（ODI）和视觉模拟量表（VAS）分析临床疗效。结果：治疗后，观察组OPG含量高于本组治疗前和电针组治疗后，差异有统计学意义（均P〈0．05）；IL-1β含量，ODI和VAS评分均低于本组治疗前和电针组治疗后，差异均有统计学意义（均P〈0．05）。结论：电针夹脊穴结合夹脊穴注射盐酸青藤碱注射液治疗老年椎体压缩性骨折腰痛的临床疗效果显著，优于单纯夹脊电针。
基金
2013年湖北省卫生厅中医药中西医结合科研项目,No.2013Z-B13.
