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清凉散联合西药治疗复发性阿弗他溃疡(胃火上炎)随机平行对照研究 被引量:1

Randomized Parallel Contrast Study on the Treatment of Stomach Fire Flaming up(胃火上炎) Recurrent Aphthous Ulcer with Traditional Prescription Qingliang Decoction(清凉散) and Western Medicine
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摘要 [目的]观察清凉散联合西药治疗复发性阿弗他溃疡(胃火上炎)疗效。[方法]使用随机平行对照方法,将86例门诊患者按就诊顺序号抽签方法随机分为两组。对照组43例口腔溃疡膜贴敷于患处;复合维生素B,2片/次,3次/d。治疗组43例清凉散(石膏~生、地黄~熟各10g,麦冬6g,牛膝、知母、黄芩各10g,黄连6g,升麻9g,甘草3g),水煎300mL,早晚饭后30min服用;西药治疗同对照组。连续治疗1个月为1疗程。观测临床症状、中医证候、不良反应。治疗1疗程(1个月),判定疗效。随访1年,观测复发率。[结果]治疗组痊愈26例,显效15例,无效2例,总有效率95.35%;对照组痊愈15例,显效15例,无效13例,总有效率69.77%;治疗组疗效优于对照组(P<0.01)。中医证候两组均有改善,治疗组改善优于对照组(P<0.01)。随访1年,复发率两组无明显差异(P>0.05)。[结论]清凉散联合西药治疗复发性阿弗他溃疡(胃火上炎),疗效满意,无严重不良反应,值得推广。 [Objective] To observe the clinical efficacy of the treatment of stomach fire flaming up recurrent aphthous ulcer with traditional Prescription Qingliang Decoction. [Method] 86 patients with stomach fire flaming up recurrent aphthous ulcer were observed and randomly divided into two groups. The patients in control group (43 cases) were treated with oral ulcer film and vitamin B complex;the patients in therapy group (43 cases) were used Traditional Chinese medicine Qingliang decoction additional to western routine therapy. The curative effectiveness was assessed after one month treatment. The recurrence rate was assessed after one year. [Result] The effective rate in therapy group is 95.35%; the effective rate in control group is 69.77%. The effective rate in therapy group increased significantly compared with the control group (P〈0.01). For the syndrome of traditional Chinese medicine, the patients in two groups both improved, but the patients in therapy group improved significantly compared with the control group (P〈0.01). And the recurrence rate shows no significant differences between two groups (P〉0.05). [Conclusion] Traditional Chinese medicine Qingliang decoction treatment for stomach fire flaming up recurrent aphthous ulcer shows effective in treatment.
作者 于春艳 YU Chunyan(Huanggu Odontopathy Therapetic Institution,Shenyang 110031,China)
出处 《实用中医内科杂志》 2018年第7期36-38,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 复发性阿弗他溃疡 口疮 胃火上炎 清凉散 口腔溃疡膜 贴敷 中医证候 随访 复发率 中药复方 随机平行对照研究 recurrent aphthous ulcer aphtha stomach fire flaming up (胃火上炎) Qingliang decoction (清凉散) oral ulcer film attach syndrome of traditional Chinese medicine follow-up visit recurrence rate Chinese herbal compound randomized parallel contrast study)
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