摘要
目的探讨缩宫素与卡前列甲酯栓对剖宫产术后产妇出血量及首次排气排尿时间的影响。方法研究对象选取陕西中医药大学第二附属医院2015年5月至2017年5月收治行剖宫产产妇共100例,采用随机数字表法分为对照组(50例)和观察组(50例),分别于术后给予缩宫素和卡前列甲酯栓治疗;比较两组产妇术后出血量,首次排气时间,首次排尿时间及不良反应发生率。结果观察组术后2 h和4 h出血量分别为(196.46±25.32)mL和(231.01±35.12)mL,对照组分别为(241.38±37.04)mL和(295.83±48.47)mL,观察者均少于对照组(t=7.079、7.657,P<0.001);观察组术后首次排气时间(24.95±3.60)h显著短于对照组(31.70±4.33)h(t=8.476,P<0.001);观察组术后<1 h、1~2 h、2~4 h、>4 h的排尿人数分别为3例、20例、24例和3例,对照组分别为7例、33例、10例和0例,秩和检验结果显示观察组整体短于对照组(Z=3.525,P<0.001)。观察组和对照组不良反应发生率分别为6.00%和4.00%,差异无统计学意义(χ~2=0.444,P=0.505)。结论相较于缩宫素,卡前列甲酯栓用于剖宫产术后产妇可有效降低术后出血量,加快胃肠功能恢复进程,实现早期排尿,且未加重药物不良反应。
Objective To investigate the effeCTs of oxytocin and carboprost methylate suppositories on postoperative bleeding and the first exhaust and miCTurition time in parturient after cesarean seCTion. Methods One hundred lying-in women were chosen in the period from May 2015 to May 2017 in The Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine. According to the randomized digital table method,they were assigned into 2 groups including control group（ 50 patients） with oxytocin and observation group（ 50 patients） with carboprost methylate suppositories after cesarean seCTion. The bleeding amount after operation,the first exhaust time,the first miCTurition time and the incidence rate of adverse reaCTions between the two groups were compared. Results The bleeding amount at 2 h and 4 h after operation of observation group were（ 196. 46 ± 25. 32） mL and（ 231. 01 ± 35. 12） mL,and the control group were（ 241. 38 ± 37. 04） mL and（ 295. 83 ± 48. 47） mL; the bleeding amount of the observation group was less than control group（ t = 7. 079,7. 657,P〈0. 001）. The first exhaust time of the observation group [（ 24. 95 ± 3. 60） h]was shorter than the control group [（ 31. 70 ± 4. 33） h]（ t = 8. 476,P〈0. 001）. The miCTurition number of observation group at less than 1 h,1 to 2 h,2 to 4 h,and more than 4 h after surgery were 3 cases,20 cases,24 cases and 33 cases,respeCTively; and the control group were 7 cases,33 cases,10 cases and no one,respeCTively Kruskal-Wallis test results showed that the miCTurition number of the observation group was shorter than the control group（ Z = 3. 525,P〈0. 001）. The incidence rates of adverse reaCTions in the observation group and control group were 6. 00% and 4. 00%,respeCTively,there was no significant difference between the two groups（ χ~2= 0. 444,P = 0. 505）. Conclusions Compared with oxytocin,carboprost methylate suppositories in the treatment of lying-in women after cesarean seCTion can efficiently reduce the amount of postoperative bleeding,speed up the recovery process of gastrointestinal funCTion,achieve the urination in early stage,and do not aggravate the adverse reaCTions of drugs.
作者
王婧
刘博
杨筱凤
WANG Qian;LIU Bo;YANG Xiaofeng(Department of Obstetrics,The Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang,Shaanxi 712000,China;Department of Gynecology,The First Affiliated Hospital of Xi＇an Jiaotong University,Xi＇an,Shaanxi 7100B1,China)
出处
《安徽医药》
CAS
2018年第10期1972-1975,共4页
Anhui Medical and Pharmaceutical Journal
基金
国家自然基金面上项目(81472428)
关键词
剖宫产术/康复
缩宫素
子宫出血
蠕动
排尿
卡前列甲酯栓
Cesarean seCTion/rehabilitation
Oxytoein
Uterine hemorrhage
Peristalsis
Urination
Carboprost methylate suppositories
