摘要
目的:探讨卡前列素氨丁三醇联合改良式B-Lynch缝扎术及限制性补液疗法对剖宫产术中产后出血患者综合治疗研究的安全性和有效性。方法:选取本院所抢救产后出血患者100例,分为对照组和观察组,每组50例,对照组采用缩宫素联合传统缝合术及传统补液法进行治疗,观察组采用卡前列素氨丁三醇联合改良式B-Lynch缝扎术及限制性补液法进行治疗。对比两组方法抢救产后出血患者的术中出血量、术后出血量、输血量,血流动力学指标及凝血功能。结果:实验研究结果表明观察组的术中出血量、术后出血量及输血量均低于对照组,观察组无出现并发症患者。观察组治疗后0.5h及2h的血流动力学指标均优于对照组,两组患者相关血流动力学指标在组间、不同时点间和组间·不同时点间的交互作用比较差异有统计学意义(P<0.05)。观察组治疗后6h及12h凝血功能优于对照组(P<0.05)。结论:卡前列素氨丁三醇联合改良式B-Lynch缝扎术及限制性补液疗法对剖宫产术中产后出血的综合治疗安全可靠。
Objective： To investigate the safety and efficacy of Comprehensive treatment of postpartum hemorrhage in caesarean section by combined modified B-Lynch suture and restrictive rehydration therapy with Carboprost Tromethamine Injection. Methods： 100 cases of postpartum hemorrhage were selected and divided into the control group and the observation group according to the different treatment methods,so there are 50 patients in each group. The control group was treated with oxytocin combined with traditional suture and traditional fluid supplement. The observation group was treated with the combination of modified B-Lynch suture and restrictive fluid filling with Carboprost Tromethamine Injection. The amount of intraoperative bleeding,postoperative bleeding,blood transfusion,hemodynamic index and coagulation function were compared between the two groups. Results： The experimental results showed that the amount of bleeding,the amount of bleeding and the amount of blood transfusion in the observation group were lower than those of the control group. There was no complication in the observation group. The hemodynamic indexes of the observation group at 0.5 h and 2 h after treatment were better than those of the control group,there were significant differences in related hemodynamic indicators between the two groups,between different time points and between groups.The difference was statistically significant（ P〈0.05）. The clotting function of the observation group was better than that of the control group at 6 h and 12 h after treatment. Conclusion： The Comprehensive treatment of postpartum hemorrhage in caesarean section by combined modified B-Lynch suture and restrictive rehydration therapy with Carboprost Tromethamine Injection is safe and reliable.
作者
沙小龙
王倩
SHA Xiaolong;WANG Qian(Maternal and Child Health Hospital Affiliated to Xuzhou Medical University,Jiangsu Xuzhou 221009,China)
出处
《河北医学》
CAS
2018年第9期1482-1486,共5页
Hebei Medicine
基金
江苏省徐州市科技局项目
(编号:KC16SL099)
