摘要
目的探讨蠲痹汤加减治疗膝骨性关节炎的临床疗效。方法将2016年6月—2017年6月90例膝骨性关节炎患者分组(随机数字表法)。对照组45例给予盐酸氨基葡萄糖胶囊、尼美舒利缓释胶囊治疗,观察组45例则给予对照组西药联合蠲痹汤加减治疗。比较2组膝骨性关节炎治疗总有效率;膝关节疼痛完全消失时间、膝关节活动恢复时间;治疗前后患者膝关节功能WOMAC评分、膝关节疼痛NRS评分;用药安全性。结果观察组治疗总有效率高于对照组,P<0.05;观察组膝关节疼痛完全消失时间、膝关节活动恢复时间优于对照组,P<0.05;治疗前2组膝关节功能WOMAC评分、膝关节疼痛NRS评分相近,P>0.05;治疗后观察组膝关节功能WOMAC评分、膝关节疼痛NRS评分优于对照组,P<0.05。观察组用药安全性和对照组无明显差异,P>0.05。结论西药联合蠲痹汤加减治疗膝骨性关节炎的应用效果确切,可有效减轻关节的疼痛度,促使关节活动功能早日恢复,且药物安全性高,值得推广应用。
Objective To study the clinical curative effect of Juanbi decoction in the treatment of knee osteoarthritis. Methods 90 patients with knee osteoarthritis in our hospital from June 2016 to June 2017 were divided into two groups by random number table method. The control group was given glucosamine hydrochloride capsules and Nimesulide sustained release capsule. The observation group was given western medicine combined with Juanbi decoction. The total effective rate was compared between the two groups. The time of complete disappearance of knee pain and recovery of knee activity before and after treatment, WOMAC score of knee joint function and NRS score of knee joint pain and medication safety was compared. Results The total effective rate of knee osteoarthfitis in the observation group was higher than that in the control group P 〈 0.05. The time of complete disappearance of knee pain and recovery of knee activity in the observation group were better than that in the control group P 〈 0.05. Before treatment, the scores of functional WOMAC score and NRS score of knee pain in the two groups were similar, P 〉 0.05. After treatment, functional WOMAC score and NRS score of knee joint pain in the observation group were better than those in the control group P 〈 0.05. There was no significant difference between the safety of the observation group and the control group P 〉 0.05. Conclusion Western medicine combined with Juanbi decoction in the treatment of knee osteoarthfitis has exactly application effect, which can effectively reduce joint pain degree, make joint activity function recover at an early date, has high drug safety, and is worthy of popularization and application.
作者
黄娟
项颖
闵翠兰
HUANG Juan, XIANG Ying, MIN Cuilan(Outpatient Department, Hongdu Hospital of Traditional Chinese Medicine, Jiangxi Province, Nanchang 330008, China)
出处
《中国中医药现代远程教育》
2018年第19期102-103,共2页
Chinese Medicine Modern Distance Education of China
关键词
蠲痹汤
膝骨性关节炎
中西医结合疗法
痹证
Juanbi decoction
knee osteoarthritis
therapy of integrated medicine
arthromyodynia
